| FREIBERGER, Tomáš, Lucie GRODECKÁ, Barbora RAVČUKOVÁ, Barbora KUŘECOVÁ, Věra POSTRÁNECKÁ, Jiří VLČEK, Jiří JARKOVSKÝ, Vojtěch THON and Jiří LITZMAN. Association of FcRn expression with lung abnormalities and IVIG catabolism in patients with common variable immunodeficiency. CLINICAL IMMUNOLOGY. Elsevier, 2010, vol. 136, No 3, p. 419-425. ISSN 1521-6616. Available from: https://dx.doi.org/10.1016/j.clim.2010.05.006. |
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@article{897947,
author = {Freiberger, Tomáš and Grodecká, Lucie and Ravčuková, Barbora and Kuřecová, Barbora and Postránecká, Věra and Vlček, Jiří and Jarkovský, Jiří and Thon, Vojtěch and Litzman, Jiří},
article_number = {3},
doi = {http://dx.doi.org/10.1016/j.clim.2010.05.006},
keywords = {Neonatal Fc receptor; FcRn; Common variable immunodeficiency; Lung disease; IVIG},
language = {eng},
issn = {1521-6616},
journal = {CLINICAL IMMUNOLOGY},
title = {Association of FcRn expression with lung abnormalities and IVIG catabolism in patients with common variable immunodeficiency},
volume = {136},
year = {2010}
}
TY - JOUR
ID - 897947
AU - Freiberger, Tomáš - Grodecká, Lucie - Ravčuková, Barbora - Kuřecová, Barbora - Postránecká, Věra - Vlček, Jiří - Jarkovský, Jiří - Thon, Vojtěch - Litzman, Jiří
PY - 2010
TI - Association of FcRn expression with lung abnormalities and IVIG catabolism in patients with common variable immunodeficiency
JF - CLINICAL IMMUNOLOGY
VL - 136
IS - 3
SP - 419-425
EP - 419-425
PB - Elsevier
SN - 15216616
KW - Neonatal Fc receptor
KW - FcRn
KW - Common variable immunodeficiency
KW - Lung disease
KW - IVIG
N2 - Patients with generalized bronchiectasis and fibrosis had lower levels of FCRN mRNA compared to patients without these complications. Moreover, FCRN mRNA levels correlated negatively with the extent of bronchiectasis and the rate of IgG decline after infusion of IVIG.Our results showed that FcRn might play a role in the development of lung structural abnormalities and in the catabolism of IVIG in patients with CVID.
ER -
FREIBERGER, Tomáš, Lucie GRODECKÁ, Barbora RAVČUKOVÁ, Barbora KUŘECOVÁ, Věra POSTRÁNECKÁ, Jiří VLČEK, Jiří JARKOVSKÝ, Vojtěch THON and Jiří LITZMAN. Association of FcRn expression with lung abnormalities and IVIG catabolism in patients with common variable immunodeficiency. \textit{CLINICAL IMMUNOLOGY}. Elsevier, 2010, vol.~136, No~3, p.~419-425. ISSN~1521-6616. Available from: https://dx.doi.org/10.1016/j.clim.2010.05.006.
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