Gold and nano-gold in medicine: overview, toxicology and
perspectives

J 2009

Gold and nano-gold in medicine: overview, toxicology and perspectives

PANYALA, Nagender Reddy; Eladia Maria PEÑA-MÉNDEZ and Josef HAVEL

Basic information

Original name

Gold and nano-gold in medicine: overview, toxicology and perspectives

Name in Czech

Zlato a nano-zlato v medicíně: přehled, toxikologie a perspektivy

Authors

PANYALA, Nagender Reddy (356 India, belonging to the institution); Eladia Maria PEÑA-MÉNDEZ and Josef HAVEL (203 Czech Republic, guarantor, belonging to the institution)

Edition

Journal of Applied Biomedicine, Czech Republic, 2009, 1214-0287

Other information

Language

English

Type of outcome

Article in a journal

Field of Study

10406 Analytical chemistry

Country of publisher

Czech Republic

Confidentiality degree

is not subject to a state or trade secret

References:

URL

RIV identification code

RIV/00216224:14310/09:00113896

Organization unit

Faculty of Science

DOI

https://doi.org/10.32725/jab.2009.008

UT WoS

000267953800002

Keywords (in Czech)

Zlatých nanočástic; zlato kvantové tečky; nanomedicínu; biomolekul, toxicity

Keywords in English

Gold nanoparticles; gold quantum dots; nanomedicine; biomolecules; toxicity

Abstract

In the original language

Nano-technology has entered the field of medicine in recent decades and many of the nanomaterials developed have already had a high impact on health care. Among nanomaterials, gold nanoparticles (GNPs) and gold quantum dots (QDs) are receiving significant attention because their unique physical, chemical and biological properties are quite different from the bulk of their counterparts. In this article, after a brief historical overview, the use of gold and nano-gold in medicine is reviewed, analyzed, and discussed. The review particularly deals with the use of GNPs and bio-conjugated GNPs in cancer treatment, drug or gene delivery, DNA detection, biomedical imaging including that of brain activity, enhancement of gene regulation, the detection of toxic metals, immuno-assays, disease detection and diagnostics, therapy and also the toxicity of gold and GNPs, etc. A number of novel applications of GNPs in medicine and perspectives of nano-gold use in medicine are also discussed.

Links

KAN101630651, research and development project

Name: Tvorba nano-vrstev a nano-povlaků na textiliích s využitím plazmových povrchových úprav za atmosférického tlaku

Investor: Academy of Sciences of the Czech Republic, Preparation of nano-films and nano-coatings on textiles using plasma surface treatment at atmospheric pressure

LC06035, research and development project

Name: Centrum biofyzikální chemie, bioelektrochemie a bioanalýzy. Nové nástroje pro genomiku, proteomiku a biomedicínu.

Investor: Ministry of Education, Youth and Sports of the CR, Centre of Biophysical Chemistry, Bioelectrochemistry and Bioanalysis. New Tools for Genomics, Proteomics and Biomedicine

Cite

PANYALA, Nagender Reddy; Eladia Maria PEÑA-MÉNDEZ and Josef HAVEL. Gold and nano-gold in medicine: overview, toxicology and perspectives. Journal of Applied Biomedicine. Czech Republic, 2009, vol. 2009, No 7, p. 75-91. ISSN 1214-0287. Available from: https://doi.org/10.32725/jab.2009.008.

@article{898370,
   author = {Panyala, Nagender Reddy and PeñaandMéndez, Eladia Maria and Havel, Josef},
   article_location = {Czech Republic},
   article_number = {7},
   doi = {https://doi.org/10.32725/jab.2009.008},
   keywords = {Gold nanoparticles; gold quantum dots; nanomedicine; biomolecules; toxicity},
   language = {eng},
   issn = {1214-0287},
   journal = {Journal of Applied Biomedicine},
   title = {Gold and nano-gold in medicine: overview, toxicology and perspectives},
   url = {https://jab.zsf.jcu.cz/pdfs/jab/2009/02/02.pdf},
   volume = {2009},
   year = {2009}
}

TY  - JOUR
ID  - 898370
AU  - Panyala, Nagender Reddy - Peña-Méndez, Eladia Maria - Havel, Josef
PY  - 2009
TI  - Gold and nano-gold in medicine: overview, toxicology and perspectives
JF  - Journal of Applied Biomedicine
VL  - 2009
IS  - 7
SP  - 75-91
EP  - 75-91
SN  - 12140287
KW  - Gold nanoparticles
KW  - gold quantum dots
KW  - nanomedicine
KW  - biomolecules
KW  - toxicity
UR  - https://jab.zsf.jcu.cz/pdfs/jab/2009/02/02.pdf
L2  - https://jab.zsf.jcu.cz/pdfs/jab/2009/02/02.pdf
N2  - Nano-technology has entered the field of medicine in recent decades and many of the nanomaterials developed have already had a high impact on health care. Among nanomaterials, gold nanoparticles (GNPs) and gold quantum dots (QDs) are receiving significant attention because their unique physical, chemical and biological properties are quite different from the bulk of their counterparts. In this article, after a brief historical overview, the use of gold and nano-gold in medicine is reviewed, analyzed, and discussed. The review particularly deals with the use of GNPs and bio-conjugated GNPs in cancer treatment, drug or gene delivery, DNA detection, biomedical imaging including that of brain activity, enhancement of gene regulation, the detection of toxic metals, immuno-assays, disease detection and diagnostics, therapy and also the toxicity of gold and GNPs, etc. A number of novel applications of GNPs in medicine and perspectives of nano-gold use in medicine are also discussed.
ER  -

PANYALA, Nagender Reddy; Eladia Maria PEÑA-MÉNDEZ and Josef HAVEL. Gold and nano-gold in medicine: overview, toxicology and perspectives. \textit{Journal of Applied Biomedicine}. Czech Republic, 2009, vol.~2009, No~7, p.~75-91. ISSN~1214-0287. Available from: https://doi.org/10.32725/jab.2009.008.

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