a 2010

Memantine inhibits CYP2D2 metabolic activity in rats, in vitro and in vivo studies.

ZENDULKA, Ondřej, Jan JUŘICA, Lucia ZAHRADNÍKOVÁ and Alexandra ŠULCOVÁ

Basic information

Original name

Memantine inhibits CYP2D2 metabolic activity in rats, in vitro and in vivo studies.

Name in Czech

Memantin inhibuje metabolickou aktivitu CYP2D2 u potkana, in vitro a in vivo studie.

Name (in English)

Memantine inhibits CYP2D2 metabolic activity in rats, in vitro and in vivo studies.

Authors

Edition

2010

Other information

Language

Czech

Type of outcome

Konferenční abstrakt

Field of Study

30104 Pharmacology and pharmacy

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

Organization unit

Faculty of Medicine

Keywords (in Czech)

memantin; fluoxetin; CYP2D2

Keywords in English

memantine; fluoxetine; CYP2D2

Tags

International impact
Změněno: 6/12/2011 10:24, doc. PharmDr. Ondřej Zendulka, Ph.D.

Abstract

ORIG EN

V originále

Memantine is an inhibitor of CYP2D2 in rats in both experimental models used and moreover the inhibition of fluoxetine was modulated by memantine administration.

In English

Memantine is an inhibitor of CYP2D2 in rats in both experimental models used and moreover the inhibition of fluoxetine was modulated by memantine administration.

Links

MSM0021622404, plan (intention)
Name: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS
Investor: Ministry of Education, Youth and Sports of the CR, The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.