Anthracycline therapy and 24-hour blood-pressure profile in
long-term survivors of childhood cancer

J 2010

Anthracycline therapy and 24-hour blood-pressure profile in long-term survivors of childhood cancer

NOVÁKOVÁ, Zuzana, Jana ŠŤASTNÁ, Klára HONZÍKOVÁ, Hana HRSTKOVÁ, Nataša HONZÍKOVÁ et. al.

Základní údaje

Originální název

Anthracycline therapy and 24-hour blood-pressure profile in long-term survivors of childhood cancer

Autoři

NOVÁKOVÁ, Zuzana (203 Česká republika, garant, domácí), Jana ŠŤASTNÁ (203 Česká republika, domácí), Klára HONZÍKOVÁ (203 Česká republika, domácí), Hana HRSTKOVÁ (203 Česká republika, domácí), Nataša HONZÍKOVÁ (203 Česká republika, domácí), Eva ZÁVODNÁ (203 Česká republika, domácí), Bohumil FIŠER (203 Česká republika, domácí) a Petr HONZÍK (203 Česká republika)

Vydání

Physiological Research, Praha, Institute of Physiology,Academy of Sciences of the Czech Republic, 2010, 0862-8408

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30105 Physiology

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 1.646

Kód RIV

RIV/00216224:14110/10:00051469

Organizační jednotka

Lékařská fakulta

UT WoS

000279049100014

Klíčová slova anglicky

anthracyclines; blood pressure; cardiotoxicity; childhood cancer; chronobiology

Příznaky

Mezinárodní význam

Změněno: 10. 4. 2012 08:56, Mgr. Michal Petr

Anotace

V originále

In our previous studies, a decreased blood pressure was reported in children treated by anthracycline (AC). The aim of this study was to assess the long-term effects of AC anticancer therapy in 45 subjects aged 13-22 years by repeated 24-hour Holter monitoring of blood pressure.It is concluded that blood pressure in 19-22 years old AC patients is lower during night hours, the age-dependent increase of blood pressure seen in healthy controls between 13 and 22 years of age does not occur in patients. This finding is consistent with the long-lasting impairment of the sympathetic nervous system caused by anthracyclines.

Návaznosti

MSM0021622402, záměr

Název: Časná diagnostika a léčba kardiovaskulárních chorob

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Časná diagnostika a léčba kardiovaskulárních chorob

Citovat

NOVÁKOVÁ, Zuzana, Jana ŠŤASTNÁ, Klára HONZÍKOVÁ, Hana HRSTKOVÁ, Nataša HONZÍKOVÁ, Eva ZÁVODNÁ, Bohumil FIŠER a Petr HONZÍK. Anthracycline therapy and 24-hour blood-pressure profile in long-term survivors of childhood cancer. Physiological Research. Praha: Institute of Physiology,Academy of Sciences of the Czech Republic, 2010, roč. 59, Suppl 1, s. "S97"-S102", 6 s. ISSN 0862-8408.

@article{900493,
   author = {Nováková, Zuzana and Šťastná, Jana and Honzíková, Klára and Hrstková, Hana and Honzíková, Nataša and Závodná, Eva and Fišer, Bohumil and Honzík, Petr},
   article_location = {Praha},
   article_number = {Suppl 1},
   keywords = {anthracyclines; blood pressure; cardiotoxicity; childhood cancer; chronobiology},
   language = {eng},
   issn = {0862-8408},
   journal = {Physiological Research},
   title = {Anthracycline therapy and 24-hour blood-pressure profile in long-term survivors of childhood cancer},
   volume = {59},
   year = {2010}
}

TY  - JOUR
ID  - 900493
AU  - Nováková, Zuzana - Šťastná, Jana - Honzíková, Klára - Hrstková, Hana - Honzíková, Nataša - Závodná, Eva - Fišer, Bohumil - Honzík, Petr
PY  - 2010
TI  - Anthracycline therapy and 24-hour blood-pressure profile in long-term survivors of childhood cancer
JF  - Physiological Research
VL  - 59
IS  - Suppl 1
SP  - "S97"-S102"
EP  - "S97"-S102"
PB  - Institute of Physiology,Academy of Sciences of the Czech Republic
SN  - 08628408
KW  - anthracyclines
KW  - blood pressure
KW  - cardiotoxicity
KW  - childhood cancer
KW  - chronobiology
N2  - In our previous studies, a decreased blood pressure was reported in children treated by anthracycline (AC). The aim of this study was to assess the long-term effects of AC anticancer therapy in 45 subjects aged 13-22 years by repeated 24-hour Holter monitoring of blood pressure.It is concluded that blood pressure in 19-22 years old AC patients is lower during night hours, the age-dependent increase of blood pressure seen in healthy controls between 13 and 22 years of age does not occur in patients. This finding is consistent with the long-lasting impairment of the sympathetic nervous system caused by anthracyclines.
ER  -

NOVÁKOVÁ, Zuzana, Jana ŠŤASTNÁ, Klára HONZÍKOVÁ, Hana HRSTKOVÁ, Nataša HONZÍKOVÁ, Eva ZÁVODNÁ, Bohumil FIŠER a Petr HONZÍK. Anthracycline therapy and 24-hour blood-pressure profile in long-term survivors of childhood cancer. \textit{Physiological Research}. Praha: Institute of Physiology,Academy of Sciences of the Czech Republic, 2010, roč.~59, Suppl 1, s.~''S97''-S102'', 6 s. ISSN~0862-8408.

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