| NOVÁKOVÁ, Zuzana, Jana ŠŤASTNÁ, Klára HONZÍKOVÁ, Hana HRSTKOVÁ, Nataša HONZÍKOVÁ, Eva ZÁVODNÁ, Bohumil FIŠER a Petr HONZÍK. Anthracycline therapy and 24-hour blood-pressure profile in long-term survivors of childhood cancer. Physiological Research. Praha: Institute of Physiology,Academy of Sciences of the Czech Republic, 2010, roč. 59, Suppl 1, s. "S97"-S102", 6 s. ISSN 0862-8408. |
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@article{900493,
author = {Nováková, Zuzana and Šťastná, Jana and Honzíková, Klára and Hrstková, Hana and Honzíková, Nataša and Závodná, Eva and Fišer, Bohumil and Honzík, Petr},
article_location = {Praha},
article_number = {Suppl 1},
keywords = {anthracyclines; blood pressure; cardiotoxicity; childhood cancer; chronobiology},
language = {eng},
issn = {0862-8408},
journal = {Physiological Research},
title = {Anthracycline therapy and 24-hour blood-pressure profile in long-term survivors of childhood cancer},
volume = {59},
year = {2010}
}
TY - JOUR
ID - 900493
AU - Nováková, Zuzana - Šťastná, Jana - Honzíková, Klára - Hrstková, Hana - Honzíková, Nataša - Závodná, Eva - Fišer, Bohumil - Honzík, Petr
PY - 2010
TI - Anthracycline therapy and 24-hour blood-pressure profile in long-term survivors of childhood cancer
JF - Physiological Research
VL - 59
IS - Suppl 1
SP - "S97"-S102"
EP - "S97"-S102"
PB - Institute of Physiology,Academy of Sciences of the Czech Republic
SN - 08628408
KW - anthracyclines
KW - blood pressure
KW - cardiotoxicity
KW - childhood cancer
KW - chronobiology
N2 - In our previous studies, a decreased blood pressure was reported in children treated by anthracycline (AC). The aim of this study was to assess the long-term effects of AC anticancer therapy in 45 subjects aged 13-22 years by repeated 24-hour Holter monitoring of blood pressure.It is concluded that blood pressure in 19-22 years old AC patients is lower during night hours, the age-dependent increase of blood pressure seen in healthy controls between 13 and 22 years of age does not occur in patients. This finding is consistent with the long-lasting impairment of the sympathetic nervous system caused by anthracyclines.
ER -
NOVÁKOVÁ, Zuzana, Jana ŠŤASTNÁ, Klára HONZÍKOVÁ, Hana HRSTKOVÁ, Nataša HONZÍKOVÁ, Eva ZÁVODNÁ, Bohumil FIŠER a Petr HONZÍK. Anthracycline therapy and 24-hour blood-pressure profile in long-term survivors of childhood cancer. \textit{Physiological Research}. Praha: Institute of Physiology,Academy of Sciences of the Czech Republic, 2010, roč.~59, Suppl 1, s.~''S97''-S102'', 6 s. ISSN~0862-8408.
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