SOUČEK, Karel, Eva SLABÁKOVÁ, Petra OVESNÁ, Alice MALENOVSKÁ, Alois KOZUBÍK and Aleš HAMPL. Growth/differentiation factor-15 is an abundant cytokine in human seminal plasma. Hum. Reprod. Oxford: Oxford University Press, 2010, vol. 25, No 12, p. 2962-71, 10 pp. ISSN 0268-1161.
Other formats:   BibTeX LaTeX RIS
Basic information
Original name Growth/differentiation factor-15 is an abundant cytokine in human seminal plasma
Authors SOUČEK, Karel (203 Czech Republic, guarantor, belonging to the institution), Eva SLABÁKOVÁ (203 Czech Republic), Petra OVESNÁ (203 Czech Republic, belonging to the institution), Alice MALENOVSKÁ (203 Czech Republic), Alois KOZUBÍK (203 Czech Republic, belonging to the institution) and Aleš HAMPL (203 Czech Republic, belonging to the institution).
Edition Hum. Reprod. Oxford, Oxford University Press, 2010, 0268-1161.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30105 Physiology
Country of publisher United Kingdom of Great Britain and Northern Ireland
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 4.357
RIV identification code RIV/00216224:14310/10:00067238
Organization unit Faculty of Science
UT WoS 000284637500008
Keywords in English Seminal plasma; Growth/Differentiation Factor 15 (GDF15/MIC1); FOXP3
Tags FOXP3, Growth/Differentiation Factor–15 (GDF-15/MIC-1), seminal plasma
Tags International impact, Reviewed
Changed by Changed by: prof. Ing. Petr Dvořák, CSc., učo 47260. Changed: 29/4/2014 09:55.
Abstract
The GDF-15 concentration in seminal plasma ranged from 0.2 to 6.6 ug/ml as determined by ELISA. Western blot analysis revealed that GDF-15 is present in the active form. In vitro cultivation of sperm cells with GDF-15 did not affect their viability or rates of apoptosis; however, it did inhibit proliferation of PBMCs and induce expression of FOXP3 in CD4+CD25+ cells.
Links
MSM0021622430, plan (intention)Name: Funkční a molekulární charakteristiky nádorových a normálních kmenových buněk - identifikace cílů pro nová terapeutika a terapeutické strategie
Investor: Ministry of Education, Youth and Sports of the CR, Functional and molecular characteristics of cancer and normal stem cells - identification of targets for novel therapeutics and therapeutic strategies
PrintDisplayed: 1/9/2024 18:07