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@proceedings{918734,
author = {Fialová, Kateřina and Kolářová, Jana and Sekora, Jiří and Tannenberg, Milan and Nováková, Marie and Provazník, Ivo},
booktitle = {Biosignal 2010},
keywords = {voltage sensitive dye; isolated heart},
language = {eng},
isbn = {978-80-214-4105-7},
title = {Electrophysiological Effects of Voltage Sensitive Dye di-4-ANNEPS in Rabbit and Guinea Pig Isolated Heart.},
year = {2010}
}
TY - CONF
ID - 918734
AU - Fialová, Kateřina - Kolářová, Jana - Sekora, Jiří - Tannenberg, Milan - Nováková, Marie - Provazník, Ivo
PY - 2010
TI - Electrophysiological Effects of Voltage Sensitive Dye di-4-ANNEPS in Rabbit and Guinea Pig Isolated Heart.
SN - 9788021441057
KW - voltage sensitive dye
KW - isolated heart
N2 - Mapping of cardiac electrical activity using voltage-sensitive dyes (VSDs) is considered to be a valuable method for electrophysiological studies. VSDs undergo changes in their electronic structure, and consequently their fluorescence spectra, in response to changes in the surrounding electric field and therefore may be used for recording of monophasic action potentials (MAPs). Staining of the heart tissue with the dye should not result in pharmacological or toxic effects. VSD di-4-ANEPPS is currently used in our laboratory for recording of MAPs in isolated hearts. This paper presents continuation of our previous study focused on examination of electrophysiological effects of this dye on rabbit and guinea pig isolated hearts. Electrograms, recorded during staining with the dye and washout from it, were compared and the types and frequency of dysrhythmias evaluated.
ER -
FIALOVÁ, Kateřina, Jana KOLÁŘOVÁ, Jiří SEKORA, Milan TANNENBERG, Marie NOVÁKOVÁ a Ivo PROVAZNÍK. Electrophysiological Effects of Voltage Sensitive Dye di-4-ANNEPS in Rabbit and Guinea Pig Isolated Heart. In \textit{Biosignal 2010}. 2010. ISBN~978-80-214-4105-7.
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