Další formáty:
BibTeX
LaTeX
RIS
@article{919164,
author = {Bergstralh, EJ and Monico, CG and Lieske, JC and Herges, RM and Langman, CB and Hoppe, B and Milliner, DS and Adey, D and Ahmed, S and Aigbe, M and Alexander, S and Anders, M and Amin, N and Ashette, M and Asplin, JR and Azam, N and Balakrishnan, N and Bhandare, S and Baum, M and Becker, B and Beckman, D and Beiken, S and Belani, S and Bellucci, A and Berkseth, R and Berry, P and Bhakta, N and Bhat, A and Bhupalam, S and Bia, M and BlydtandHansen, T and Bousquet, R and Braun, M and Brewer, E and Brueggmeyer, C and Bunchman, T and Butani, L and Cadnapaphornchai, M and CastilloandVelarde Lima, E and Choi, MJ and Chybowski, M and Cuitarese, F and Copelovitch, L and Corbin, F and Corey, H and Creemers, D and Cunnigham, R and Dalinghaus, K and Davis, I and de Souza, C and DeBeukalear, M and Delaney, V and Devarajan, P and Doležel, Zdeněk and Doll, HA and Douville, P and Ecklund, S},
article_location = {Atlanta},
article_number = {11},
keywords = {primary hyperoxaluria transplantation diagnose},
language = {eng},
issn = {1600-6135},
journal = {American Journal of Transplantattion},
title = {Transplantation outcomes in primary hyperoxaluria},
volume = {10},
year = {2010}
}
TY - JOUR
ID - 919164
AU - Bergstralh, EJ - Monico, CG - Lieske, JC - Herges, RM - Langman, CB - Hoppe, B - Milliner, DS - Adey, D - Ahmed, S - Aigbe, M - Alexander, S - Anders, M - Amin, N - Ashette, M - Asplin, JR - Azam, N - Balakrishnan, N - Bhandare, S - Baum, M - Becker, B - Beckman, D - Beiken, S - Belani, S - Bellucci, A - Berkseth, R - Berry, P - Bhakta, N - Bhat, A - Bhupalam, S - Bia, M - Blydt-Hansen, T - Bousquet, R - Braun, M - Brewer, E - Brueggmeyer, C - Bunchman, T - Butani, L - Cadnapaphornchai, M - Castillo-Velarde Lima, E - Choi, MJ - Chybowski, M - Cuitarese, F - Copelovitch, L - Corbin, F - Corey, H - Creemers, D - Cunnigham, R - Dalinghaus, K - Davis, I - de Souza, C - DeBeukalear, M - Delaney, V - Devarajan, P - Doležel, Zdeněk - Doll, HA - Douville, P - Ecklund, S
PY - 2010
TI - Transplantation outcomes in primary hyperoxaluria
JF - American Journal of Transplantattion
VL - 10
IS - 11
SP - 2493-2501
EP - 2493-2501
PB - Wiley-Blackwell
SN - 16006135
KW - primary hyperoxaluria transplantation diagnose
N2 - Optimal transplantation strategies are uncertain in primary hyperoxaluria (PH) due to potential for recurrent oxalosis. Outcomes of different transplantation approaches were compared using life-table methods to determine kidney graft survival among 203 patients in the International Primary Hyperoxaluria Registry. From 1976-2009, 84 kidney alone (K) and combined kidney and liver (K + L) transplants were performed in 58 patients. Among 58 first kidney transplants (32 K, 26 K + L), 1-, 3- and 5-year kidney graft survival was 82%, 68% and 49%. Renal graft loss occurred in 26 first transplants due to oxalosis in ten, chronic allograft nephropathy in six, rejection in five and other causes in five. Delay in PH diagnosis until after transplant favored early graft loss (p = 0.07). K + L had better kidney graft outcomes than K with death-censored graft survival 95% versus 56% at 3 years (p = 0.011). Among 29 year 2000-09 first transplants (24 K + L), 84% were functioning at 3 years compared to 55% of earlier transplants (p = 0.05). At 6.8 years after transplantation, 46 of 58 patients are living (43 with functioning grafts). Outcomes of transplantation in PH have improved over time, with recent K + L transplantation highly successful. Recurrent oxalosis accounted for a minority of kidney graft losses. Optimal transplantation strategies are uncertain in primary hyperoxaluria (PH) due to potential for recurrent oxalosis. Outcomes of different transplantation approaches were compared using life-table methods to determine kidney graft survival among 203 patients in the International Primary Hyperoxaluria Registry. From 1976-2009, 84 kidney alone (K) and combined kidney and liver (K + L) transplants were performed in 58 patients. Among 58 first kidney transplants (32 K, 26 K + L), 1-, 3- and 5-year kidney graft survival was 82%, 68% and 49%. Renal graft loss occurred in 26 first transplants due to oxalosis in ten, chronic allograft nephropathy in six, rejection in five and other causes in five. Delay in PH diagnosis until after transplant favored early graft loss (p = 0.07). K + L had better kidney graft outcomes than K with death-censored graft survival 95% versus 56% at 3 years (p = 0.011). Among 29 year 2000-09 first transplants (24 K + L), 84% were functioning at 3 years compared to 55% of earlier transplants (p = 0.05). At 6.8 years after transplantation, 46 of 58 patients are living (43 with functioning grafts). Outcomes of transplantation in PH have improved over time, with recent K + L transplantation highly successful. Recurrent oxalosis accounted for a minority of kidney graft losses. Impact Factor 6.433
ER -
BERGSTRALH, EJ, CG MONICO, JC LIESKE, RM HERGES, CB LANGMAN, B HOPPE a DS MILLINER. Transplantation outcomes in primary hyperoxaluria. \textit{American Journal of Transplantattion}. Atlanta: Wiley-Blackwell, 2010, roč.~10, č.~11, s.~2493-2501. ISSN~1600-6135.
|
