The effect of cortical repetitive transcranial magnetic
stimulation on cognitive event-related potentials recorded in
the subthalamic nucleus.

J 2010

The effect of cortical repetitive transcranial magnetic stimulation on cognitive event-related potentials recorded in the subthalamic nucleus.

BALÁŽ, Marek, Hana SROVNALOVÁ, Irena REKTOROVÁ a Ivan REKTOR

Základní údaje

Originální název

The effect of cortical repetitive transcranial magnetic stimulation on cognitive event-related potentials recorded in the subthalamic nucleus.

Autoři

BALÁŽ, Marek (703 Slovensko, garant, domácí), Hana SROVNALOVÁ (203 Česká republika, domácí), Irena REKTOROVÁ (203 Česká republika, domácí) a Ivan REKTOR (203 Česká republika, domácí)

Vydání

Experimental Brain Research, Springer Verlag, 2010, 0014-4819

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30000 3. Medical and Health Sciences

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 2.296

Kód RIV

RIV/00216224:14110/10:00046774

Organizační jednotka

Lékařská fakulta

UT WoS

000277712500008

Klíčová slova anglicky

inferior frontal cortex; subthalamic nucleus; executive functions; ERP; P3; hyperdirect pathway

Změněno: 20. 1. 2011 16:20, prof. MUDr. Irena Rektorová, Ph.D.

Anotace

V originále

We studied whether the cognitive event-related potentials (ERP) in the subthalamic nucleus (STN) are modified by the modulation of the inferior frontal cortex (IFC) and the dorsolateral prefrontal cortex (DLPFC) with repetitive transcranial magnetic stimulation (rTMS). Eighteen patients with Parkinson disease who had been implanted with a deep brain stimulation (DBS) electrode were included in the study. The ERPs were recorded from the DBS electrode before and after the rTMS (1 Hz, 600 pulses) over either the right IFC (10 patients) or right DLPFC (8 patients). rTMS over the right IFC led to a shortening of ERP latencies from 277 ms (SD) to 252 ms in the standard protocol and from 296 ms to 270 ms in the protocol modified by a higher load of executive functions. Connections (the IFC-STN hyperdirect pathway) with the cortex that bypass the BG-thalamocortical circuitries could explain the position of the STN in the processing of executive functions.

Návaznosti

MSM0021622404, záměr

Název: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS

Citovat

BALÁŽ, Marek, Hana SROVNALOVÁ, Irena REKTOROVÁ a Ivan REKTOR. The effect of cortical repetitive transcranial magnetic stimulation on cognitive event-related potentials recorded in the subthalamic nucleus. Experimental Brain Research. Springer Verlag, 2010, roč. 203/2010, č. 2, 11 s. ISSN 0014-4819.

@article{919493,
   author = {Baláž, Marek and Srovnalová, Hana and Rektorová, Irena and Rektor, Ivan},
   article_number = {2},
   keywords = {inferior frontal cortex; subthalamic nucleus; executive functions; ERP; P3; hyperdirect pathway},
   language = {eng},
   issn = {0014-4819},
   journal = {Experimental Brain Research},
   title = {The effect of cortical repetitive transcranial magnetic stimulation on cognitive event-related potentials recorded in the subthalamic nucleus.},
   volume = {203/2010},
   year = {2010}
}

TY  - JOUR
ID  - 919493
AU  - Baláž, Marek - Srovnalová, Hana - Rektorová, Irena - Rektor, Ivan
PY  - 2010
TI  - The effect of cortical repetitive transcranial magnetic stimulation on cognitive event-related potentials recorded in the subthalamic nucleus.
JF  - Experimental Brain Research
VL  - 203/2010
IS  - 2
PB  - Springer Verlag
SN  - 00144819
KW  - inferior frontal cortex
KW  - subthalamic nucleus
KW  - executive functions
KW  - ERP
KW  - P3
KW  - hyperdirect pathway
N2  - We studied whether the cognitive event-related potentials (ERP) in the subthalamic nucleus (STN) are modified by the modulation of the inferior frontal cortex (IFC) and the dorsolateral prefrontal cortex (DLPFC) with repetitive transcranial magnetic stimulation (rTMS). Eighteen patients with Parkinson disease who had been implanted with a deep brain stimulation (DBS) electrode were included in the study. The ERPs were recorded from the DBS electrode before and after the rTMS (1 Hz, 600 pulses) over either the right IFC (10 patients) or right DLPFC (8 patients). rTMS over the right IFC led to a shortening of ERP latencies from 277 ms (SD) to 252 ms in the standard protocol and from 296 ms to 270 ms in the protocol modified by a higher load of executive functions. Connections (the IFC-STN hyperdirect pathway) with the cortex that bypass the BG-thalamocortical circuitries could explain the position of the STN in the processing of executive functions.
ER  -

BALÁŽ, Marek, Hana SROVNALOVÁ, Irena REKTOROVÁ a Ivan REKTOR. The effect of cortical repetitive transcranial magnetic stimulation on cognitive event-related potentials recorded in the subthalamic nucleus. \textit{Experimental Brain Research}. Springer Verlag, 2010, roč.~203/2010, č.~2, 11 s. ISSN~0014-4819.

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