Relationship between high aortic pulse pressure and extension
of coronary atherosclerosis in males

J 2011

Relationship between high aortic pulse pressure and extension of coronary atherosclerosis in males

PAŘENICA, Jiří, Petr KALA, Jiří JARKOVSKÝ, Martin POLOCZEK, Otakar BOČEK et. al.

Základní údaje

Originální název

Relationship between high aortic pulse pressure and extension of coronary atherosclerosis in males

Autoři

PAŘENICA, Jiří (203 Česká republika, garant, domácí), Petr KALA (203 Česká republika, domácí), Jiří JARKOVSKÝ (203 Česká republika, domácí), Martin POLOCZEK (203 Česká republika, domácí), Otakar BOČEK (203 Česká republika, domácí), Petr JEŘÁBEK (203 Česká republika, domácí), Petr NEUGEBAUER (203 Česká republika, domácí), Miroslav VYTISKA (703 Slovensko, domácí), Ilona PARENICOVA (203 Česká republika), D. TOMCIKOVA (203 Česká republika), Monika PÁVKOVÁ GOLDBERGOVÁ (203 Česká republika, domácí) a Jindřich ŠPINAR (203 Česká republika, domácí)

Vydání

Physiological Research, AV ČR, Institute of Physiology, 2011, 0862-8408

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 1.555

Kód RIV

RIV/00216224:14110/11:00065759

Organizační jednotka

Lékařská fakulta

UT WoS

000288563800005

Klíčová slova anglicky

aortic pulse pressure; coronary atherosclerosis; males

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 28. 4. 2014 15:38, Ing. Mgr. Věra Pospíšilíková

Anotace

V originále

A high pulse pressure (PP) is a marker of increased artery stiffness and represents a well - established independent predictor for cardiovascular morbidity and mortality. The objective of the research was to determine whether invasively measured central aortic PP was related to the presence and severity of coronary artery disease. In total 1075 consecutive stable male patients undergoing diagnostic coronary angiography with a preserved left ventricular function were included. Diseased coronary vessel (DCV) was defined by the presence of > 50% stenosis. Results: Men were divided into 3 groups according to the increased value of PP. The average PP in the tertils was 47.8+-7.1 vs. 67.0+-4.9 vs. 91.3+-12.8 mm Hg (p<0,01). The significant differences of DCV was found among tertils (1.51+-1.11 vs 1.80+-1.04 vs. 1.99+-0.98 DCV, p<0.01). Aortic PP together with age and hyperlipoproteinemia were found as factors with an independent relationship to DCV according to multivariate linear regression. Conclusion: the increased value of aortic PP in the male population is independently connected with more severe atherosclerosis evaluated by the significant number of DCV.

Návaznosti

NR9356, projekt VaV

Název: Komplexní zhodnocení vlivu polymorfismu matrix metalloproteináz-1,2,3,9, tkáńového inhibitoru matrix metaloproteináz-1 a ACE na remodelaci levé komory a střednědobou prognózu po akutním infarktu mykardu s ST elevacemi léčeném primární PCI

Investor: Ministerstvo zdravotnictví ČR, Komplexní zhodnocení vlivu polymorfismu matrix metalloproteináz-1,2,3,9, tkáńového inhibitoru matrix metaloproteináz-1 a ACE na remodelaci levé komory a střednědobou prognózu po akutním infarktu mykardu s ST elevacemi léčeném primární PCI

Citovat

PAŘENICA, Jiří, Petr KALA, Jiří JARKOVSKÝ, Martin POLOCZEK, Otakar BOČEK, Petr JEŘÁBEK, Petr NEUGEBAUER, Miroslav VYTISKA, Ilona PARENICOVA, D. TOMCIKOVA, Monika PÁVKOVÁ GOLDBERGOVÁ a Jindřich ŠPINAR. Relationship between high aortic pulse pressure and extension of coronary atherosclerosis in males. Physiological Research. AV ČR, Institute of Physiology, 2011, roč. 60, č. 1, s. 47-53. ISSN 0862-8408.

@article{919826,
   author = {Pařenica, Jiří and Kala, Petr and Jarkovský, Jiří and Poloczek, Martin and Boček, Otakar and Jeřábek, Petr and Neugebauer, Petr and Vytiska, Miroslav and Parenicova, Ilona and Tomcikova, D. and Pávková Goldbergová, Monika and Špinar, Jindřich},
   article_number = {1},
   keywords = {aortic pulse pressure; coronary atherosclerosis; males},
   language = {eng},
   issn = {0862-8408},
   journal = {Physiological Research},
   title = {Relationship between high aortic pulse pressure and extension of coronary atherosclerosis in males},
   volume = {60},
   year = {2011}
}

TY  - JOUR
ID  - 919826
AU  - Pařenica, Jiří - Kala, Petr - Jarkovský, Jiří - Poloczek, Martin - Boček, Otakar - Jeřábek, Petr - Neugebauer, Petr - Vytiska, Miroslav - Parenicova, Ilona - Tomcikova, D. - Pávková Goldbergová, Monika - Špinar, Jindřich
PY  - 2011
TI  - Relationship between high aortic pulse pressure and extension of coronary atherosclerosis in males
JF  - Physiological Research
VL  - 60
IS  - 1
SP  - 47-53
EP  - 47-53
PB  - AV ČR, Institute of Physiology
SN  - 08628408
KW  - aortic pulse pressure
KW  - coronary atherosclerosis
KW  - males
N2  - A high pulse pressure (PP) is a marker of increased artery stiffness and represents a well - established independent predictor for cardiovascular morbidity and mortality. The objective of the research was to determine whether invasively measured central aortic PP was related to the presence and severity of coronary artery disease. In total 1075 consecutive stable male patients undergoing diagnostic coronary angiography with a preserved left ventricular function were included. Diseased coronary vessel (DCV) was defined by the presence of > 50% stenosis. Results: Men were divided into 3 groups according to the increased value of PP. The average PP in the tertils was 47.8+-7.1 vs. 67.0+-4.9 vs. 91.3+-12.8 mm Hg (p<0,01). The significant differences of DCV was found among tertils (1.51+-1.11 vs 1.80+-1.04 vs. 1.99+-0.98 DCV, p<0.01). Aortic PP together with age and hyperlipoproteinemia were found as factors with an independent relationship to DCV according to multivariate linear regression. Conclusion: the increased value of aortic PP in the male population is independently connected with more severe atherosclerosis evaluated by the significant number of DCV.
ER  -

PAŘENICA, Jiří, Petr KALA, Jiří JARKOVSKÝ, Martin POLOCZEK, Otakar BOČEK, Petr JEŘÁBEK, Petr NEUGEBAUER, Miroslav VYTISKA, Ilona PARENICOVA, D. TOMCIKOVA, Monika PÁVKOVÁ GOLDBERGOVÁ a Jindřich ŠPINAR. Relationship between high aortic pulse pressure and extension of coronary atherosclerosis in males. \textit{Physiological Research}. AV ČR, Institute of Physiology, 2011, roč.~60, č.~1, s.~47-53. ISSN~0862-8408.

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