2010
Tectonic penetrating keratoplasty and sclerokeratoplasty as treatment for perforated corneal ulcers of different aetiology
HLINOMAZOVÁ, Zuzana, Eva VLKOVÁ a Monika HORÁČKOVÁZákladní údaje
Originální název
Tectonic penetrating keratoplasty and sclerokeratoplasty as treatment for perforated corneal ulcers of different aetiology
Název česky
Tektonická keratoplastika a sclerokeratoplastika v léčbě rohovkových penetrujících vředů různé etiologie
Název anglicky
Tectonic penetrating keratoplasty and sclerokeratoplasty as treatment for perforated corneal ulcers of different aetiology
Autoři
HLINOMAZOVÁ, Zuzana (203 Česká republika, garant, domácí), Eva VLKOVÁ (203 Česká republika, domácí) a Monika HORÁČKOVÁ (203 Česká republika, domácí)
Vydání
XXVIII. Congres of ESCRS, 2010
Další údaje
Jazyk
čeština
Typ výsledku
Konferenční abstrakt
Obor
30200 3.2 Clinical medicine
Stát vydavatele
Česká republika
Utajení
není předmětem státního či obchodního tajemství
Odkazy
Kód RIV
RIV/00216224:14110/10:00040869
Organizační jednotka
Lékařská fakulta
Klíčová slova česky
Tektonická keratoplastika; rohovkový vřed
Klíčová slova anglicky
Tectonic keratoplasty; corneal ucer
Změněno: 20. 1. 2011 17:25, doc. MUDr. Zuzana Hlinomazová, Ph.D.
V originále
PURPOSE: To report the clinical outcomes in patient with herpetic, bacterial and autoimmune corneal ulcers treated by tectonic, centric or eccentric penetrating keratoplasty or by tectonic sclerokeratoplasty. DESIGN: Nonrandomized clinical trial. METHODS: The study included 37 patients (37 eyes) with perforated corneal ulcers consecutively operated by two surgeons. The main patients age was 62 years (SD 7). The patients were divided into 3 groups. Group A - keratolysis in herpes eye disease, 12 patients (32%), group B - keratolysis in autoimmune diseases (rheumatoid arthritis, Wegener granulomatosis 14 patients (37%) and group C - keratolysis in bacterial corneal ulcers 11 patients (31%). The time of observation was 12 to 42 months (SD 28). BCVA and immunologic graft rejection was assessed after 3 months. All patients have used systemic immunosupression CSA and MFM during 12 to 32 months(median 16). RESULTS: Values of BCVA were comparable during first 3 months in all groups, ranged from light perception to 0.4 (median 0.1). All transplants were clear, decreased visual acuity was due to cataract. In this period immunological graft rejection was not found in any group. After 12 month BCVA was in group A light perception to 0.1(median 0.01) in group B light perception to 0.1 (median 0.09), in group C light perception to 0.6 (median 0.1). Total immunological graft rejection after 12 month was found in group A in 100%, in group B in 50%and in group C in 15%. CONCLUSIONS: Tectonic penetrating keratoplasty is a treatment with uncertain results mainly in herpetic diseases of the eye. In other indications, such as bacterial ulcers and autoimmune systemic diseases, can keratolysis lead to good functional results.
Anglicky
URPOSE: To report the clinical outcomes in patient with herpetic, bacterial and autoimmune corneal ulcers treated by tectonic, centric or eccentric penetrating keratoplasty or by tectonic sclerokeratoplasty. DESIGN: Nonrandomized clinical trial. METHODS: The study included 37 patients (37 eyes) with perforated corneal ulcers consecutively operated by two surgeons. The main patients age was 62 years (SD 7). The patients were divided into 3 groups. Group A - keratolysis in herpes eye disease, 12 patients (32%), group B - keratolysis in autoimmune diseases (rheumatoid arthritis, Wegener granulomatosis 14 patients (37%) and group C - keratolysis in bacterial corneal ulcers 11 patients (31%). The time of observation was 12 to 42 months (SD 28). BCVA and immunologic graft rejection was assessed after 3 months. All patients have used systemic immunosupression CSA and MFM during 12 to 32 months(median 16). RESULTS: Values of BCVA were comparable during first 3 months in all groups, ranged from light perception to 0.4 (median 0.1). All transplants were clear, decreased visual acuity was due to cataract. In this period immunological graft rejection was not found in any group. After 12 month BCVA was in group A light perception to 0.1(median 0.01) in group B light perception to 0.1 (median 0.09), in group C light perception to 0.6 (median 0.1). Total immunological graft rejection after 12 month was found in group A in 100%, in group B in 50%and in group C in 15%. CONCLUSIONS: Tectonic penetrating keratoplasty is a treatment with uncertain results mainly in herpetic diseases of the eye. In other indications, such as bacterial ulcers and autoimmune systemic diseases, can keratolysis lead to good functional results.
Návaznosti
| NR8507, projekt VaV |
|