Detailed Information on Publication Record
2010
Importance of screening of IgG anti-IgA antibodies in hypogammaglobulinemic subjects to prevent anaphylactoid reactions
THON, VojtěchBasic information
Original name
Importance of screening of IgG anti-IgA antibodies in hypogammaglobulinemic subjects to prevent anaphylactoid reactions
Name in Czech
Význam vyšetření IgG anti-IgA protilátek k prevenci anafylaktoidní reakce u hypogamaglobulinémií
Authors
THON, Vojtěch (203 Czech Republic, guarantor, belonging to the institution)
Edition
Klinická imunológia a alergológia, 2010, 1335-0013
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30102 Immunology
Country of publisher
Slovakia
Confidentiality degree
není předmětem státního či obchodního tajemství
RIV identification code
RIV/00216224:14110/10:00058965
Organization unit
Faculty of Medicine
Keywords (in Czech)
anti-IgA protilátky; anafylaktoidní reakce; hypogamaglobulinémie
Keywords in English
anti-IgA antibodies; anaphylactoid reaction; hypogammaglobulinemia
Tags
International impact, Reviewed
Změněno: 21/4/2013 11:29, Ing. Mgr. Věra Pospíšilíková
V originále
Anti-IgA antibodies can cause severe anaphylactoid reactions in the case of blood transfusion or substitution immunoglobulin therapy in patients with hypogammaglobulinemia. We found a significant amount of anti-IgA antibodies in 10 % of patients with the most common primary hypogammaglobulinemia (selective IgA deficiency and common variable immunodeficiencies) where the serum IgA level was lower than 0.05 g/L. Knowledge of the presence of antibodies against IgA is important in clinical practice in order to prevent an anaphylactic reaction during blood transfusion or during immunoglobulin substitution therapy.
In Czech
Vyšetření přítomnosti anti-IgA protilátlek je důležité pro prevenci anafylaktoidní reakce v případě podání krevních transfúzí nebo substituční léčby imunoglobulinovými preparáty.
Links
| 7E08062, research and development project |
|