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@article{921785,
author = {Thon, Vojtěch},
article_number = {3},
keywords = {anti-IgA antibodies; anaphylactoid reaction; hypogammaglobulinemia},
language = {eng},
issn = {1335-0013},
journal = {Klinická imunológia a alergológia},
title = {Importance of screening of IgG anti-IgA antibodies in hypogammaglobulinemic subjects to prevent anaphylactoid reactions},
volume = {20},
year = {2010}
}
TY - JOUR
ID - 921785
AU - Thon, Vojtěch
PY - 2010
TI - Importance of screening of IgG anti-IgA antibodies in hypogammaglobulinemic subjects to prevent anaphylactoid reactions
JF - Klinická imunológia a alergológia
VL - 20
IS - 3
SP - 26-27
EP - 26-27
SN - 13350013
KW - anti-IgA antibodies
KW - anaphylactoid reaction
KW - hypogammaglobulinemia
N2 - Anti-IgA antibodies can cause severe anaphylactoid reactions in the case of blood transfusion or substitution immunoglobulin therapy in patients with hypogammaglobulinemia. We found a significant amount of anti-IgA antibodies in 10 % of patients with the most common primary hypogammaglobulinemia (selective IgA deficiency and common variable immunodeficiencies) where the serum IgA level was lower than 0.05 g/L. Knowledge of the presence of antibodies against IgA is important in clinical practice in order to prevent an anaphylactic reaction during blood transfusion or during immunoglobulin substitution therapy.
ER -
THON, Vojtěch. Importance of screening of IgG anti-IgA antibodies in hypogammaglobulinemic subjects to prevent anaphylactoid reactions. \textit{Klinická imunológia a alergológia}. 2010, vol.~20, No~3, p.~26-27. ISSN~1335-0013.
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