EFNS guidelines for the diagnosis and management of Alzheimers
disease

J 2010

EFNS guidelines for the diagnosis and management of Alzheimers disease

HORT, J., JT. O BRIEN, G. GAINOTTI, T. PIRTTILA, BO. POPESCU et. al.

Základní údaje

Originální název

EFNS guidelines for the diagnosis and management of Alzheimers disease

Název česky

EFNS doporučení pro diagnostiku a léčbu Alzheimerovy nemoci

Autoři

HORT, J. (203 Česká republika), JT. O BRIEN (826 Velká Británie a Severní Irsko), G. GAINOTTI (380 Itálie), T. PIRTTILA (246 Finsko), BO. POPESCU (642 Rumunsko), Irena REKTOROVÁ (203 Česká republika, domácí), S. SORBI (380 Itálie) a P. SCHELTENS (528 Nizozemské království, garant)

Vydání

European Journal of Neurology, 2010, 1351-5101

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30000 3. Medical and Health Sciences

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 3.765

Kód RIV

RIV/00216224:14110/10:00047014

Organizační jednotka

Lékařská fakulta

UT WoS

000281799200006

Klíčová slova anglicky

Alzheimers disease; dementia; diagnosis; guideline; management; review; treatment

Změněno: 20. 1. 2011 23:28, prof. MUDr. Irena Rektorová, Ph.D.

Anotace

V originále

The aim of this revised international guideline was to present a peer-reviewed evidence-based statement for the guidance of practice for clinical neurologists, geriatricians, psychiatrists, and other specialist physicians responsible for the care of patients with AD. Mild cognitive impairment and non- Alzheimer dementias are not included in this guideline. Methods: The task force working group reviewed evidence from original research articles, meta-analysis, and systematic reviews, published before May 2009. The evidence was classified and consensus recommendations graded (A, B, or C) according to the EFNS guidance. Where there was a lack of evidence, but clear consensus, good practice points were provided. Results: The recommendations for clinical diagnosis, blood tests, neuropsychology, neuroimaging, electroencephalography, cerebrospinal fluid (CSF) analysis, genetic testing, disclosure of diagnosis, treatment of AD, behavioural and psychological symptoms in dementia, legal issues, counselling and support for caregivers were all revised as compared with the previous EFNS guideline. Conclusion: A number of new recommendations and good practice points are made, namely in CSF, neuropsychology, neuroimaging and reviewing non-evidence based therapies. The assessment, interpretation, and treatment of symptoms, disability, needs, and caregiver stress during the course of AD require the contribution of many different professionals. These professionals should adhere to these guideline to improve the diagnosis and management of AD.

Návaznosti

MSM0021622404, záměr

Název: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS

Citovat

HORT, J., JT. O BRIEN, G. GAINOTTI, T. PIRTTILA, BO. POPESCU, Irena REKTOROVÁ, S. SORBI a P. SCHELTENS. EFNS guidelines for the diagnosis and management of Alzheimers disease. European Journal of Neurology. 2010, roč. 17, č. 10, s. 1236-1248. ISSN 1351-5101.

@article{921804,
   author = {Hort, J. and O Brien, JT. and Gainotti, G. and Pirttila, T. and Popescu, BO. and Rektorová, Irena and Sorbi, S. and Scheltens, P.},
   article_number = {10},
   keywords = {Alzheimers disease; dementia; diagnosis; guideline; management; review; treatment},
   language = {eng},
   issn = {1351-5101},
   journal = {European Journal of Neurology},
   title = {EFNS guidelines for the diagnosis and management of Alzheimers disease},
   volume = {17},
   year = {2010}
}

TY  - JOUR
ID  - 921804
AU  - Hort, J. - O Brien, JT. - Gainotti, G. - Pirttila, T. - Popescu, BO. - Rektorová, Irena - Sorbi, S. - Scheltens, P.
PY  - 2010
TI  - EFNS guidelines for the diagnosis and management of Alzheimers disease
JF  - European Journal of Neurology
VL  - 17
IS  - 10
SP  - 1236-1248
EP  - 1236-1248
SN  - 13515101
KW  - Alzheimers disease
KW  - dementia
KW  - diagnosis
KW  - guideline
KW  - management
KW  - review
KW  - treatment
N2  - The aim of this revised international guideline was to present a peer-reviewed evidence-based statement for the guidance of practice for clinical neurologists, geriatricians, psychiatrists, and other specialist physicians responsible for the care of patients with AD. Mild cognitive impairment and non- Alzheimer dementias are not included in this guideline. Methods: The task force working group reviewed evidence from original research articles, meta-analysis, and systematic reviews, published before May 2009. The evidence was classified and consensus recommendations graded (A, B, or C) according to the EFNS guidance. Where there was a lack of evidence, but clear consensus, good practice points were provided. Results: The recommendations for clinical diagnosis, blood tests, neuropsychology, neuroimaging, electroencephalography, cerebrospinal fluid (CSF) analysis, genetic testing, disclosure of diagnosis, treatment of AD, behavioural and psychological symptoms in dementia, legal issues, counselling and support for caregivers were all revised as compared with the previous EFNS guideline. Conclusion: A number of new recommendations and good practice points are made, namely in CSF, neuropsychology, neuroimaging and reviewing non-evidence based therapies. The assessment, interpretation, and treatment of symptoms, disability, needs, and caregiver stress during the course of AD require the contribution of many different professionals. These professionals should adhere to these guideline to improve the diagnosis and management of AD.
ER  -

HORT, J., JT. O BRIEN, G. GAINOTTI, T. PIRTTILA, BO. POPESCU, Irena REKTOROVÁ, S. SORBI a P. SCHELTENS. EFNS guidelines for the diagnosis and management of Alzheimers disease. \textit{European Journal of Neurology}. 2010, roč.~17, č.~10, s.~1236-1248. ISSN~1351-5101.

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