OLSSON, AG, P PAUCIULLO, Vladimír SOŠKA, P LULEY, RE PIETERS, G BRODA and B PALACIOS. Comparison of the efficacy and tolerability of fluvastatin extended-release and immediate-release formulations in the treatment of primary hypercholesterolemia: a randomized trial. Clin Ther. UNITED STATES: ELSEVIER, 2001, vol. 23, No 1, p. 45-61. ISSN 0149-2918. |
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@article{930411, author = {Olsson, AG and Pauciullo, P and Soška, Vladimír and Luley, P and Pieters, RE and Broda, G and Palacios, B}, article_location = {UNITED STATES}, article_number = {1}, keywords = {Fluvastatin; hypercholesterolemia}, issn = {0149-2918}, journal = {Clin Ther}, title = {Comparison of the efficacy and tolerability of fluvastatin extended-release and immediate-release formulations in the treatment of primary hypercholesterolemia: a randomized trial.}, volume = {23}, year = {2001} }
TY - JOUR ID - 930411 AU - Olsson, AG - Pauciullo, P - Soška, Vladimír - Luley, P - Pieters, RE - Broda, G - Palacios, B PY - 2001 TI - Comparison of the efficacy and tolerability of fluvastatin extended-release and immediate-release formulations in the treatment of primary hypercholesterolemia: a randomized trial. JF - Clin Ther VL - 23 IS - 1 SP - 45-61 EP - 45-61 PB - ELSEVIER SN - 01492918 KW - Fluvastatin KW - hypercholesterolemia N2 - The purpose of this study was to compare the lipid-lowering efficacy and tolerability of fluvastatin ER (80 mg once daily) versus fluvastatin immediate-release (IR) (40 mg once or twice daily). Of the 1183 patients enrolled, 695 were randomly assigned to treatment 346 to fluvastatin ER 80 mg QPM, 174 to fluvastatin IR 40 mg QPM, and 175 to fluvastatin IR 40 mg BID. Patients were well matched between groups, with a mean age of 56 years and body mass index of 27 kg/m2; 56.0% of patients (389/695) were female and 97.7% (679/695) were white. Fluvastatin ER 80 mg QPM lowered LDL-C levels significantly ER -
OLSSON, AG, P PAUCIULLO, Vladimír SOŠKA, P LULEY, RE PIETERS, G BRODA and B PALACIOS. Comparison of the efficacy and tolerability of fluvastatin extended-release and immediate-release formulations in the treatment of primary hypercholesterolemia: a randomized trial. \textit{Clin Ther}. UNITED STATES: ELSEVIER, 2001, vol.~23, No~1, p.~45-61. ISSN~0149-2918.
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