Combined exposure to cyanobacterial biomass, lead and the
Newcastle virus enhances avian toxicity

J 2010

Combined exposure to cyanobacterial biomass, lead and the Newcastle virus enhances avian toxicity

PIKULA, Jiří, Hana BANĎOUCHOVÁ, Klára HILSCHEROVÁ, Veronika PAŠKOVÁ, Jana SEDLÁČKOVÁ et. al.

Základní údaje

Originální název

Combined exposure to cyanobacterial biomass, lead and the Newcastle virus enhances avian toxicity

Autoři

PIKULA, Jiří (203 Česká republika, garant), Hana BANĎOUCHOVÁ (203 Česká republika), Klára HILSCHEROVÁ (203 Česká republika, domácí), Veronika PAŠKOVÁ (203 Česká republika, domácí), Jana SEDLÁČKOVÁ (203 Česká republika), Ondřej ADAMOVSKÝ (203 Česká republika, domácí), Zora KNOTKOVÁ (203 Česká republika), Petr LANÝ (203 Česká republika), Jiří MACHÁT (203 Česká republika, domácí), Blahoslav MARŠÁLEK (203 Česká republika, domácí), Ladislav NOVOTNÝ (203 Česká republika), Miroslav POHANKA (203 Česká republika) a František VITULA (203 Česká republika)

Vydání

Science of the Total Environment, AMSTERDAM, NETHERLANDS, ELSEVIER SCIENCE BV, 2010, 0048-9697

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10511 Environmental sciences

Stát vydavatele

Nizozemské království

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 3.190

Kód RIV

RIV/00216224:14310/10:00052042

Organizační jednotka

Přírodovědecká fakulta

DOI

http://dx.doi.org/10.1016/j.scitotenv.2010.07.050

UT WoS

000282348100010

Klíčová slova anglicky

Multiple stressors; Birds; Japanese quail model; Microcystin; Heavy metals; Sublethal exposure

Štítky

rivok, ZR

Změněno: 20. 4. 2012 10:14, Ing. Andrea Mikešková

Anotace

V originále

This experimental study was successful in testing the hypothesis that adverse effects of cyanotoxins, heavy metals and a non-pathogenic immunological challenge combine to enhance avian toxicity. Mortality occurred in combined exposures to naturally occurring cyanobacterial biomass and lead shots, lead shots and Newcastle vaccination as well as in single lead shot exposure. Mostly acute effects around day 10 were observed. On day 30 of exposure, there were no differences in the liver accumulation of lead in single and combined exposure groups. Interestingly, liver microcystin levels were elevated in birds co-exposed to cyanobacterial biomass together with lead or lead and the Newcastle virus. Significant differences in body weights between all Pb-exposed and Pb-non-exposed birds were found on days 10 and 20. Single exposure to cyanobacterial biomass resulted in hepatic vacuolar dystrophy, whereas co-exposure with lead led to more severe granular dystrophy. Haematological changes were associated with lead exposure, in particular. Biochemical analysis revealed a decrease in glucose and an increase in lactate dehydrogenase in single and combined cyanobacterial and lead exposures, which also showed a decreased antibody response to vaccination.

Návaznosti

MSM0021622412, záměr

Název: Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální, regionální a lokální úrovni (INCHEMBIOL) (Akronym: INCHEMBIOL)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální , regionální a lokální úrovni

Citovat

PIKULA, Jiří, Hana BANĎOUCHOVÁ, Klára HILSCHEROVÁ, Veronika PAŠKOVÁ, Jana SEDLÁČKOVÁ, Ondřej ADAMOVSKÝ, Zora KNOTKOVÁ, Petr LANÝ, Jiří MACHÁT, Blahoslav MARŠÁLEK, Ladislav NOVOTNÝ, Miroslav POHANKA a František VITULA. Combined exposure to cyanobacterial biomass, lead and the Newcastle virus enhances avian toxicity. Science of the Total Environment. AMSTERDAM, NETHERLANDS: ELSEVIER SCIENCE BV, 2010, roč. 408, č. 21, s. 4984-4992. ISSN 0048-9697. Dostupné z: https://dx.doi.org/10.1016/j.scitotenv.2010.07.050.

@article{932302,
   author = {Pikula, Jiří and Banďouchová, Hana and Hilscherová, Klára and Pašková, Veronika and Sedláčková, Jana and Adamovský, Ondřej and Knotková, Zora and Laný, Petr and Machát, Jiří and Maršálek, Blahoslav and Novotný, Ladislav and Pohanka, Miroslav and Vitula, František},
   article_location = {AMSTERDAM, NETHERLANDS},
   article_number = {21},
   doi = {http://dx.doi.org/10.1016/j.scitotenv.2010.07.050},
   keywords = {Multiple stressors; Birds; Japanese quail model; Microcystin; Heavy metals; Sublethal exposure},
   language = {eng},
   issn = {0048-9697},
   journal = {Science of the Total Environment},
   title = {Combined exposure to cyanobacterial biomass, lead and the Newcastle virus enhances avian toxicity},
   volume = {408},
   year = {2010}
}

TY  - JOUR
ID  - 932302
AU  - Pikula, Jiří - Banďouchová, Hana - Hilscherová, Klára - Pašková, Veronika - Sedláčková, Jana - Adamovský, Ondřej - Knotková, Zora - Laný, Petr - Machát, Jiří - Maršálek, Blahoslav - Novotný, Ladislav - Pohanka, Miroslav - Vitula, František
PY  - 2010
TI  - Combined exposure to cyanobacterial biomass, lead and the Newcastle virus enhances avian toxicity
JF  - Science of the Total Environment
VL  - 408
IS  - 21
SP  - 4984-4992
EP  - 4984-4992
PB  - ELSEVIER SCIENCE BV
SN  - 00489697
KW  - Multiple stressors
KW  - Birds
KW  - Japanese quail model
KW  - Microcystin
KW  - Heavy metals
KW  - Sublethal exposure
N2  - This experimental study was successful in testing the hypothesis that adverse effects of cyanotoxins, heavy metals and a non-pathogenic immunological challenge combine to enhance avian toxicity. Mortality occurred in combined exposures to naturally occurring cyanobacterial biomass and lead shots, lead shots and Newcastle vaccination as well as in single lead shot exposure. Mostly acute effects around day 10 were observed. On day 30 of exposure, there were no differences in the liver accumulation of lead in single and combined exposure groups. Interestingly, liver microcystin levels were elevated in birds co-exposed to cyanobacterial biomass together with lead or lead and the Newcastle virus. Significant differences in body weights between all Pb-exposed and Pb-non-exposed birds were found on days 10 and 20. Single exposure to cyanobacterial biomass resulted in hepatic vacuolar dystrophy, whereas co-exposure with lead led to more severe granular dystrophy. Haematological changes were associated with lead exposure, in particular. Biochemical analysis revealed a decrease in glucose and an increase in lactate dehydrogenase in single and combined cyanobacterial and lead exposures, which also showed a decreased antibody response to vaccination.
ER  -

PIKULA, Jiří, Hana BANĎOUCHOVÁ, Klára HILSCHEROVÁ, Veronika PAŠKOVÁ, Jana SEDLÁČKOVÁ, Ondřej ADAMOVSKÝ, Zora KNOTKOVÁ, Petr LANÝ, Jiří MACHÁT, Blahoslav MARŠÁLEK, Ladislav NOVOTNÝ, Miroslav POHANKA a František VITULA. Combined exposure to cyanobacterial biomass, lead and the Newcastle virus enhances avian toxicity. \textit{Science of the Total Environment}. AMSTERDAM, NETHERLANDS: ELSEVIER SCIENCE BV, 2010, roč.~408, č.~21, s.~4984-4992. ISSN~0048-9697. Dostupné z: https://dx.doi.org/10.1016/j.scitotenv.2010.07.050.

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