2010
Enhancement of toxicity of selected POPs and its mixtures in consequence of interaction with dissolved organic matter
BITTNER, Michal, Petra MACÍKOVÁ a John P. GIESYZákladní údaje
Originální název
Enhancement of toxicity of selected POPs and its mixtures in consequence of interaction with dissolved organic matter
Název česky
Zvýšení toxicity vybraných POPs a jejich směsí v důsledku interakce s rozpuštěnou organickou hmotou
Autoři
BITTNER, Michal, Petra MACÍKOVÁ a John P. GIESY
Vydání
SETAC EUROPE 20th Annual Meeting, 23-27 May 2010, Seville, Spain. In Abstract Book, p. 240. 2010
Další údaje
Jazyk
angličtina
Typ výsledku
Konferenční abstrakt
Obor
10511 Environmental sciences
Stát vydavatele
Španělsko
Utajení
není předmětem státního či obchodního tajemství
Organizační jednotka
Přírodovědecká fakulta
Klíčová slova anglicky
Dissolved organic matter, Humic substances, Ah-receptor, In vitro bioassay, Co-exposure, Mixtures, Dioxin
Změněno: 29. 3. 2011 15:18, Mgr. Petra Labohá, Ph.D.
Anotace
V originále
In waters, dissolved organic matter (DOM) is ubiquitous mixture of individual organic compounds, and humic substances (HS, about 70 % of DOM) that are products of humification process that forms HS from dead organic matter. In our previous in vitro study, we described the interaction (positive or negative) of various DOM/HS samples with aryl hydrocarbon receptor (AhR, also known as dioxin receptor). In this paper, we summarize our new findings on interaction of both AhR-active and -inactive DOM/HS with various persistent organic pollutants (POPs), such as polychlorinated biphenyls, polychlorinated dioxin and polycyclic aromatic hydrocarbons, and their mixtures. Results have shown mostly enhancement or no change of AhR-mediated activity of POPs if co-exposed with DOM/HS. Possible interpretation of the observed results will be discussed. This research has been supported by project GAČR 525/08/P464.
Návaznosti
GP525/08/P464, projekt VaV |
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