IZAKOVIČOVÁ HOLLÁ, Lydie, Kristína MUSILOVÁ, Jan VOKURKA, Pavla PANTUČKOVÁ, Lubomír KUKLA, Martina KUKLETOVÁ and Zdeněk BROUKAL. Gene polymorphisms in gingivitis. In Gingival Diseases - Their Aetiology, Prevention and Treatment. 1. vydání. Rijeka: INTECH, 2011, p. 203-230. ISBN 978-953-307-376-7.
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Basic information
Original name Gene polymorphisms in gingivitis
Name in Czech Genové polymorfizmy u gingivitidy
Authors IZAKOVIČOVÁ HOLLÁ, Lydie (203 Czech Republic, guarantor, belonging to the institution), Kristína MUSILOVÁ (203 Czech Republic, belonging to the institution), Jan VOKURKA (203 Czech Republic, belonging to the institution), Pavla PANTUČKOVÁ (203 Czech Republic, belonging to the institution), Lubomír KUKLA (203 Czech Republic, belonging to the institution), Martina KUKLETOVÁ (203 Czech Republic, belonging to the institution) and Zdeněk BROUKAL (203 Czech Republic, belonging to the institution).
Edition 1. vydání. Rijeka, Gingival Diseases - Their Aetiology, Prevention and Treatment, p. 203-230, 28 pp. 2011.
Publisher INTECH
Other information
Original language English
Type of outcome Chapter(s) of a specialized book
Field of Study 30200 3.2 Clinical medicine
Country of publisher Croatia
Confidentiality degree is not subject to a state or trade secret
WWW URL
RIV identification code RIV/00216224:14110/11:00052207
Organization unit Faculty of Medicine
ISBN 978-953-307-376-7
Keywords (in Czech) gingivitida; genový polymorfizmus; parodontitida; zánět; děti
Keywords in English gingivitis; gene polymorphism; periodontitis; inflammation; children
Tags Reviewed
Changed by Changed by: Mgr. Michal Petr, učo 65024. Changed: 15/4/2012 11:23.
Abstract
1) We aimed to conduct a review of the literature for gene polymorphisms associated with susceptibility to gingivitis. We searched the studies in English language using the key words gingivitis and gene (mutation or polymorphism) and analyzed their results. (a) Firstly, in introduction, etiopathogenesis and clinical picture of gingivitis were discussed, the role of genetics in this disease was analyzed and different approaches for genetic studies described. (b) Secondly, candidate genes in relation to gingivitis were analyzed and discussed in relation to various carriage rates of the rare (R)-allele, different environmental and other risk factors. 2) In addition, new data (still unpublished) about the role of interleukin-18 (IL-18) gene polymorphisms at positions -607C/A (rs1946518), -137G/C (rs187238) and -133C/G (rs360721) in relation to gingivitis and microbial pathogens in Czech children are presented in this chapter.
Links
NT11405, research and development projectName: Mikrobiologické a genetické determinanty rozvoje a progrese parodontitidy u diabetiků 1. a 2. typu a jejich reciproční vztah ke kompenzaci diabetu
Investor: Ministry of Health of the CR
1M0528, research and development projectName: Stomatologické výzkumné centrum
Investor: Ministry of Education, Youth and Sports of the CR, Dental research centre
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