Impulse Control Disorders in patients with Parkinson’s Disease

GESCHEIDT, Tomáš and Martin BAREŠ. Impulse Control Disorders in patients with Parkinson’s Disease. Acta Neurologica Belgica. 2011, vol. 111, No 1, p. 3-9. ISSN 0300-9009.

Basic information

• Original name: Impulse Control Disorders in patients with Parkinson’s Disease
• Authors: GESCHEIDT, Tomáš (203 Czech Republic, belonging to the institution) and Martin BAREŠ (203 Czech Republic, guarantor, belonging to the institution).
• Edition: Acta Neurologica Belgica, 2011, 0300-9009.

Other information

• Original language: English
• Type of outcome: Article in a journal
• Field of Study: 30000 3. Medical and Health Sciences
• Country of publisher: Belgium
• Confidentiality degree: is not subject to a state or trade secret
• Impact factor: Impact factor: 0.535
• RIV identification code: RIV/00216224:14110/11:00052316
• Organization unit: Faculty of Medicine
• UT WoS: 000289009500002
• Keywords in English: Parkinson’s disease; impulse control disorders; pathological gambling; hypersexuality; punding; dopamine dysregulation syndrome; dopaminergic agonists
• Tags: International impact

Abstract

In patients with Parkinson’s disease with higher prevalence than in current population there appear pathological behaviours characterized by compulsion, repetitiveness and impulsivity, which are connected with material profit or pleasurable experience. They are, in particular, pathological gambling, hypersexuality, compulsive shopping and compulsive eating (in the literature they are collectively referred to as impulse control disorders). Pathological preoccupation with repeated mechanical activities (so-called punding) and excessive compulsive intake of dopaminergic medication (so-called dopamine dysregulation syndrome or also syndrome of hedonistic homeostatic dysregulation) are of similar nature. The paper treats briefly the risk factors and prevalence of these pathological behaviours. In current clinical practice, these psychiatric complications frequently escape doctors’ attention, they are underdiagnosed. Although no generally valid recommendations for their therapy are currently available, they can be influenced medically. Of advantage can be modified dopaminergic medication (usually dose reduction of dopaminergic agonists); multidisciplinary approach to the problem is appropriate. The pathological behaviours given above can frequently lead to considerable material losses and markedly aggravate patients’ handicap in the social sphere; it can be expected that in the future they can become a problem also from the ethical and legal points of view.

Links

• MSM0021622404, plan (intention): Name: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS

Investor: Ministry of Education, Youth and Sports of the CR, The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.