a 2011

POTENTIOMETRIC AND VOLTAMMETRIC STUDY OF 6 – BENZYLAMINOPURINE AND ITS DERIVATIVES

PILAŘOVÁ, Iveta, Zdeňka BALCAROVÁ, Přemysl LUBAL and Libuše TRNKOVÁ

Basic information

Original name

POTENTIOMETRIC AND VOLTAMMETRIC STUDY OF 6 – BENZYLAMINOPURINE AND ITS DERIVATIVES

Authors

PILAŘOVÁ, Iveta (203 Czech Republic, belonging to the institution), Zdeňka BALCAROVÁ (203 Czech Republic, belonging to the institution), Přemysl LUBAL (203 Czech Republic, belonging to the institution) and Libuše TRNKOVÁ (203 Czech Republic, guarantor, belonging to the institution)

Edition

XXI INTERNATIONAL SYMPOSIUM ON BIOELECTROCHEMISTRY AND BIOENERGETICS, 2011

Other information

Language

English

Type of outcome

Konferenční abstrakt

Field of Study

10403 Physical chemistry

Country of publisher

Poland

Confidentiality degree

není předmětem státního či obchodního tajemství

RIV identification code

RIV/00216224:14310/11:00052408

Organization unit

Faculty of Science

ISBN

978-83-62139-23-1

Keywords in English

6-BAP;cytokinins;potentiometry;cyclic voltammetry;elimination voltammetry

Tags

Změněno: 13/4/2012 12:41, prof. RNDr. Libuše Trnková, CSc.

Abstract

V originále

Benzylaminopurine (6–BAP),as the derivative of adenine,is involved among cytokinins (CKs).CKs are phytohormones which participate in regulation of growth and development processes of plants. Methoxy and chlorine derivatives of 6-BAP show antitumor activity (inhibitors of cyclin–dependent kinases) and due to this effect may be considered as potential cytostatics.The aim of this contribution is the determination of protonation constants of 6–BAP and its derivatives by potentiometric method for the different experimental conditions,such as methanol content (2.5-20 v/v percentages),temperature (5-37C) and ionic strength (I=0.1-1M NaCl).To determine the thermodynamic parameters deltaH and deltaS the temperature dependence of pKa was employed.The effect of the position of methoxy and chlorine group (X is Cl or OCH3) in 2',3'and 4'on benzene ring of 6–BAP was studied,too.6–BAP and its derivatives were also studied using cyclic voltammetry and elimination voltammetry with linear scan (EVLS) and it was found,that addition of methanol in measured solution supported adsorption of above–mentioned ligands on mercury electrode.

Links

LC06035, research and development project
Name: Centrum biofyzikální chemie, bioelektrochemie a bioanalýzy. Nové nástroje pro genomiku, proteomiku a biomedicínu.
Investor: Ministry of Education, Youth and Sports of the CR, Centre of Biophysical Chemistry, Bioelectrochemistry and Bioanalysis. New Tools for Genomics, Proteomics and Biomedicine
MSM0021622412, plan (intention)
Name: Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální, regionální a lokální úrovni (INCHEMBIOL) (Acronym: INCHEMBIOL)
Investor: Ministry of Education, Youth and Sports of the CR, Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)
MUNI/A/0992/2009, interní kód MU
Name: Vývoj metodologie a instrumentace analytické chemie pro studium složení a vlastností přírodních a syntetických materiálů (Acronym: MIA)
Investor: Masaryk University, Category A