POTENTIOMETRIC AND VOLTAMMETRIC STUDY OF 6 – BENZYLAMINOPURINE AND ITS DERIVATIVES

PILAŘOVÁ, Iveta, Zdeňka BALCAROVÁ, Přemysl LUBAL and Libuše TRNKOVÁ. POTENTIOMETRIC AND VOLTAMMETRIC STUDY OF 6 – BENZYLAMINOPURINE AND ITS DERIVATIVES. In XXI INTERNATIONAL SYMPOSIUM ON BIOELECTROCHEMISTRY AND BIOENERGETICS. 2011. ISBN 978-83-62139-23-1.

Basic information

• Original name: POTENTIOMETRIC AND VOLTAMMETRIC STUDY OF 6 – BENZYLAMINOPURINE AND ITS DERIVATIVES
• Authors: PILAŘOVÁ, Iveta (203 Czech Republic, belonging to the institution), Zdeňka BALCAROVÁ (203 Czech Republic, belonging to the institution), Přemysl LUBAL (203 Czech Republic, belonging to the institution) and Libuše TRNKOVÁ (203 Czech Republic, guarantor, belonging to the institution).
• Edition: XXI INTERNATIONAL SYMPOSIUM ON BIOELECTROCHEMISTRY AND BIOENERGETICS, 2011.

Other information

• Original language: English
• Type of outcome: Conference abstract
• Field of Study: 10403 Physical chemistry
• Country of publisher: Poland
• Confidentiality degree: is not subject to a state or trade secret
• RIV identification code: RIV/00216224:14310/11:00052408
• Organization unit: Faculty of Science
• ISBN: 978-83-62139-23-1
• Keywords in English: 6-BAP;cytokinins;potentiometry;cyclic voltammetry;elimination voltammetry
• Tags: AKR

Abstract

Benzylaminopurine (6–BAP),as the derivative of adenine,is involved among cytokinins (CKs).CKs are phytohormones which participate in regulation of growth and development processes of plants. Methoxy and chlorine derivatives of 6-BAP show antitumor activity (inhibitors of cyclin–dependent kinases) and due to this effect may be considered as potential cytostatics.The aim of this contribution is the determination of protonation constants of 6–BAP and its derivatives by potentiometric method for the different experimental conditions,such as methanol content (2.5-20 v/v percentages),temperature (5-37C) and ionic strength (I=0.1-1M NaCl).To determine the thermodynamic parameters deltaH and deltaS the temperature dependence of pKa was employed.The effect of the position of methoxy and chlorine group (X is Cl or OCH3) in 2',3'and 4'on benzene ring of 6–BAP was studied,too.6–BAP and its derivatives were also studied using cyclic voltammetry and elimination voltammetry with linear scan (EVLS) and it was found,that addition of methanol in measured solution supported adsorption of above–mentioned ligands on mercury electrode.

Links

• LC06035, research and development project: Name: Centrum biofyzikální chemie, bioelektrochemie a bioanalýzy. Nové nástroje pro genomiku, proteomiku a biomedicínu.

Investor: Ministry of Education, Youth and Sports of the CR, Centre of Biophysical Chemistry, Bioelectrochemistry and Bioanalysis. New Tools for Genomics, Proteomics and Biomedicine

• MSM0021622412, plan (intention): Name: Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální, regionální a lokální úrovni (INCHEMBIOL) (Acronym: INCHEMBIOL)

Investor: Ministry of Education, Youth and Sports of the CR, Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)

• MUNI/A/0992/2009, interní kód MU: Name: Vývoj metodologie a instrumentace analytické chemie pro studium složení a vlastností přírodních a syntetických materiálů (Acronym: MIA)

Investor: Masaryk University, Category A