Levels of PCDDs/Fs, dl-PCBs, PCNs and PBDEs were investigated in the case study focused on temporal and spatial variability of the POP levels in river sediments. The sediment samples were collected from 5 sampling sites (4 riverine, 1 oxbow) from the rivershed of Morava river on monthly basis during the period of one year. This region, heavily affected by various industrial activities as well as intensive agriculture, is a subject of frequent flood events