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@article{945516,
author = {Čupera, Jakub and Lánský, Petr},
article_number = {416},
doi = {http://dx.doi.org/10.1016/j.ijpharm.2011.05.081},
keywords = {Dissolution; Sigmoidal profile; Random lag time; Dissolution variability},
language = {eng},
issn = {0378-5173},
journal = {International Journal of Pharmaceutics},
title = {Homogeneous diffusion layer model of dissolution incorporating the initial transient phase},
url = {http://dx.doi.org/10.1016/j.ijpharm.2011.05.081},
volume = {2011},
year = {2011}
}
TY - JOUR
ID - 945516
AU - Čupera, Jakub - Lánský, Petr
PY - 2011
TI - Homogeneous diffusion layer model of dissolution incorporating the initial transient phase
JF - International Journal of Pharmaceutics
VL - 2011
IS - 416
SP - 35-42
EP - 35-42
SN - 03785173
KW - Dissolution
KW - Sigmoidal profile
KW - Random lag time
KW - Dissolution variability
UR - http://dx.doi.org/10.1016/j.ijpharm.2011.05.081
L2 - http://dx.doi.org/10.1016/j.ijpharm.2011.05.081
N2 - We considered random lag time before the homogeneous phase of the dissolution begins. The resulting dissolution profiles are characterized by sigmoidal shape commonly observed in empirical dissolution data. Furthermore, probability distribution of repeated measurements at fixed time is deduced from the model and function describing variability of the data in dependency on time is proposed.
ER -
ČUPERA, Jakub a Petr LÁNSKÝ. Homogeneous diffusion layer model of dissolution incorporating the initial transient phase. \textit{International Journal of Pharmaceutics}. 2011, roč.~2011, č.~416, s.~35-42. ISSN~0378-5173. Dostupné z: https://dx.doi.org/10.1016/j.ijpharm.2011.05.081.
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