Repetitive transcranial magnetic stimulation (rTMS) in the treatment of depressive disorder

USTOHAL, Libor, Radovan PŘIKRYL, Hana PŘIKRYLOVÁ KUČEROVÁ and Eva ČEŠKOVÁ. Repetitive transcranial magnetic stimulation (rTMS) in the treatment of depressive disorder. Activitas Nervosa Superior Rediviva. Praha: Collegium Internationale Activitatis N.S, vol. 53, No 1, p. 3-13. ISSN 1337-933X. 2011.

Basic information

• Original name: Repetitive transcranial magnetic stimulation (rTMS) in the treatment of depressive disorder
• Name in Czech: Repetitivní transkraniální magnetická stimulace (rTMS) v léčbě depresivní poruchy
• Authors: USTOHAL, Libor (203 Czech Republic, guarantor, belonging to the institution), Radovan PŘIKRYL (203 Czech Republic, belonging to the institution), Hana PŘIKRYLOVÁ KUČEROVÁ (203 Czech Republic, belonging to the institution) and Eva ČEŠKOVÁ (203 Czech Republic, belonging to the institution).
• Edition: Activitas Nervosa Superior Rediviva, Praha, Collegium Internationale Activitatis N.S, 2011, 1337-933X.

Other information

• Original language: English
• Type of outcome: Article in a journal
• Field of Study: 30000 3. Medical and Health Sciences
• Country of publisher: Czech Republic
• Confidentiality degree: is not subject to a state or trade secret
• WWW: URL
• RIV identification code: RIV/00216224:14740/11:00053538
• Organization unit: Central European Institute of Technology
• Keywords (in Czech): rTMS; stimulace; depresivní porucha, mechanismus účinku; účinnost; přezkoumání
• Keywords in English: rTMS; stimulation; depressive disorder; mechanism of action; effectiveness; review
• Tags: ok, rivok
• Tags: Reviewed

Abstract

This article deals with the use of repetitive transcranial magnetic stimulation (rTMS) in the treatment of depressive disorder. The method involves influencing the brain using variable magnetic field. Repetitive TMS is safe, well-tolerated and has very few adverse effects. It is the treatment of depressive disorder where psychiatrists have most experience with this method which, however, is starting to be used for the therapy of other mental disorders as well. Repetitive transcranial magnetic stimulation has been proven to influence cortical excitability and the metabolic activity of neurons. Many studies of its effectiveness in the treatment of depressive disorder have been performed to date and can be divided into three generations. The results of different studies have been summarised in several meta-analyses; the most recent ones in particular show that rTMS constitutes a promising therapeutic method, although a number of questions concerning mainly the exact mechanism of its action, the setting of the most appropriate stimulation parameters and the selection of the most susceptible patients remain unanswered.

Links

• MSM0021622404, plan (intention): Name: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS

Investor: Ministry of Education, Youth and Sports of the CR, The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.