a 2011

Interleukin-1 gene variations in post-orthodontic external root resorption

LINHARTOVÁ, Petra, Pavlína ČERNOCHOVÁ, Martina RAUDENSKÁ, Jolana LIPKOVÁ, Lydie IZAKOVIČOVÁ HOLLÁ et. al.

Basic information

Original name

Interleukin-1 gene variations in post-orthodontic external root resorption

Authors

Edition

XV. celostátní konference DNA diagnostiky. Praha, 2011

Other information

Type of outcome

Konferenční abstrakt

Confidentiality degree

není předmětem státního či obchodního tajemství

Organization unit

Faculty of Medicine

Abstract

V originále

External apical root resorption (EARR) is a permanent shortening of the end of the tooth root. EARR is a common clinical complication of orthodontic treatment and is known to occur after trauma and in response to inflammation. Polymorphisms in the interleukin-1 (IL-1) genes play a role in the inflammatory diseases through the modulation of cytokine levels. The aim of this study was to associate two single nucleotide polymorphisms (SNPs) and one variable number of tandem repeats (VNTR) polymorphism in IL-1 with EARR in the Czech population. This study was supported by projects 1M0528 and IGA NT11405-6.

Links

NT11405, research and development project
Name: Mikrobiologické a genetické determinanty rozvoje a progrese parodontitidy u diabetiků 1. a 2. typu a jejich reciproční vztah ke kompenzaci diabetu
Investor: Ministry of Health of the CR
1M0528, research and development project
Name: Stomatologické výzkumné centrum
Investor: Ministry of Education, Youth and Sports of the CR, Dental research centre