Is the Cerebellum a Potential Target for Stimulation in
Parkinson's Disease? Results of 1-Hz rTMS on Upper Limb Motor
Tasks

J 2011

Is the Cerebellum a Potential Target for Stimulation in Parkinson's Disease? Results of 1-Hz rTMS on Upper Limb Motor Tasks

MINKS, Eduard, Radek MAREČEK, Tomáš PAVLÍK, Petra OVESNÁ, Martin BAREŠ et. al.

Základní údaje

Originální název

Is the Cerebellum a Potential Target for Stimulation in Parkinson's Disease? Results of 1-Hz rTMS on Upper Limb Motor Tasks

Autoři

MINKS, Eduard (203 Česká republika, garant, domácí), Radek MAREČEK (203 Česká republika, domácí), Tomáš PAVLÍK (203 Česká republika, domácí), Petra OVESNÁ (203 Česká republika, domácí) a Martin BAREŠ (203 Česká republika, domácí)

Vydání

Cerebellum, 2011, 1473-4222

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30000 3. Medical and Health Sciences

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 3.207

Kód RIV

RIV/00216224:14110/11:00054073

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1007/s12311-011-0290-1

UT WoS

000297123900018

Klíčová slova anglicky

Cerebellum; Motor system; Parkinson's disease; rTMS;TMS;Transcranial magnetic stimulation

Příznaky

Mezinárodní význam

Změněno: 20. 4. 2012 12:06, Mgr. Michal Petr

Anotace

V originále

The aim of this study was to find whether 1-Hz cerebellar repetitive transcranial magnetic stimulation (rTMS) could affect upper limb movement in early-stage Parkinson's disease (PD). Twenty patients with PD underwent one session with real and one with sham rTMS. rTMS (1 Hz, 600 pulses) was targeted at the right lateral cerebellum. Before and after rTMS, patients performed two motor tests with their fingers and hands (ball test, nine-hole peg test). The duration of these tests was measured. There were statistically significant differences (p<0.05) in the results of the tests after real stimulation and sham stimulation. We excluded the impact of learning. After real rTMS, we observed a significantly faster response in the ball test and a slower response in the nine-hole peg test, both on the right upper limb. This study indicates the influence of 1-Hz cerebellar rTMS in modifying the voluntary movements of the upper limb in PD. This influence is differentiated: the improvement of gross motor skills and the worsening of fine motor skills.

Návaznosti

MSM0021622404, záměr

Název: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS

Citovat

MINKS, Eduard, Radek MAREČEK, Tomáš PAVLÍK, Petra OVESNÁ a Martin BAREŠ. Is the Cerebellum a Potential Target for Stimulation in Parkinson's Disease? Results of 1-Hz rTMS on Upper Limb Motor Tasks. Cerebellum. 2011, roč. 10, č. 4, s. 804–811. ISSN 1473-4222. Dostupné z: https://dx.doi.org/10.1007/s12311-011-0290-1.

@article{959849,
   author = {Minks, Eduard and Mareček, Radek and Pavlík, Tomáš and Ovesná, Petra and Bareš, Martin},
   article_number = {4},
   doi = {http://dx.doi.org/10.1007/s12311-011-0290-1},
   keywords = {Cerebellum; Motor system; Parkinson's disease; rTMS;TMS;Transcranial magnetic stimulation},
   language = {eng},
   issn = {1473-4222},
   journal = {Cerebellum},
   title = {Is the Cerebellum a Potential Target for Stimulation in Parkinson's Disease? Results of 1-Hz rTMS on Upper Limb Motor Tasks},
   volume = {10},
   year = {2011}
}

TY  - JOUR
ID  - 959849
AU  - Minks, Eduard - Mareček, Radek - Pavlík, Tomáš - Ovesná, Petra - Bareš, Martin
PY  - 2011
TI  - Is the Cerebellum a Potential Target for Stimulation in Parkinson's Disease? Results of 1-Hz rTMS on Upper Limb Motor Tasks
JF  - Cerebellum
VL  - 10
IS  - 4
SP  - 804–811
EP  - 804–811
SN  - 14734222
KW  - Cerebellum
KW  - Motor system
KW  - Parkinson's disease
KW  - rTMS;TMS;Transcranial magnetic stimulation
N2  - The aim of this study was to find whether 1-Hz cerebellar repetitive transcranial magnetic stimulation (rTMS) could affect upper limb movement in early-stage Parkinson's disease (PD). Twenty patients with PD underwent one session with real and one with sham rTMS. rTMS (1 Hz, 600 pulses) was targeted at the right lateral cerebellum. Before and after rTMS, patients performed two motor tests with their fingers and hands (ball test, nine-hole peg test). The duration of these tests was measured. There were statistically significant differences (p<0.05) in the results of the tests after real stimulation and sham stimulation. We excluded the impact of learning. After real rTMS, we observed a significantly faster response in the ball test and a slower response in the nine-hole peg test, both on the right upper limb. This study indicates the influence of 1-Hz cerebellar rTMS in modifying the voluntary movements of the upper limb in PD. This influence is differentiated: the improvement of gross motor skills and the worsening of fine motor skills.
ER  -

MINKS, Eduard, Radek MAREČEK, Tomáš PAVLÍK, Petra OVESNÁ a Martin BAREŠ. Is the Cerebellum a Potential Target for Stimulation in Parkinson's Disease? Results of 1-Hz rTMS on Upper Limb Motor Tasks. \textit{Cerebellum}. 2011, roč.~10, č.~4, s.~804–811. ISSN~1473-4222. Dostupné z: https://dx.doi.org/10.1007/s12311-011-0290-1.

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