KRUPKOVÁ, Olga, Jindřiška HAMMEROVÁ, Tereza VACLOVÁ a Stjepan ULDRIJAN. P38 MAPK - a Potential Target for Metastatic Melanoma Therapy? In European Multidisciplinary Cancer Congress on Integrating Basic and Translational Science, Surgery, Radiotherapy, Medical oncology, Advocacy and Care. 2011. ISSN 0959-8049. |
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@proceedings{962402, author = {Krupková, Olga and Hammerová, Jindřiška and Vaclová, Tereza and Uldrijan, Stjepan}, booktitle = {European Multidisciplinary Cancer Congress on Integrating Basic and Translational Science, Surgery, Radiotherapy, Medical oncology, Advocacy and Care}, keywords = {melanoma p38 MAPK targeted therapy autophagy}, language = {eng}, title = {P38 MAPK - a Potential Target for Metastatic Melanoma Therapy?}, year = {2011} }
TY - CONF ID - 962402 AU - Krupková, Olga - Hammerová, Jindřiška - Vaclová, Tereza - Uldrijan, Stjepan PY - 2011 TI - P38 MAPK - a Potential Target for Metastatic Melanoma Therapy? KW - melanoma p38 MAPK targeted therapy autophagy N2 - We have shown previously, that a small molecular inhibitor of p38 MAPK SB202190 (SB) selectively induces autophagy in MM cell lines, but not in other cell types we tested. We have demonstrated that SB-induced autophagy promotes cell survival and combining SB with autophagy inhibitors can lead to a significant decrease of MM cell viability. ER -
KRUPKOVÁ, Olga, Jindřiška HAMMEROVÁ, Tereza VACLOVÁ a Stjepan ULDRIJAN. P38 MAPK - a Potential Target for Metastatic Melanoma Therapy? In \textit{European Multidisciplinary Cancer Congress on Integrating Basic and Translational Science, Surgery, Radiotherapy, Medical oncology, Advocacy and Care}. 2011. ISSN~0959-8049.
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