Enhanced osteoblast and osteoclast responses to a thin film
sputtered hydroxyapatite coating

J 2011

Enhanced osteoblast and osteoclast responses to a thin film sputtered hydroxyapatite coating

HAO, J., S. KURODA, K. OHYA, Sonia BARTÁKOVÁ, H. AOKI et. al.

Základní údaje

Originální název

Enhanced osteoblast and osteoclast responses to a thin film sputtered hydroxyapatite coating

Autoři

HAO, J. (392 Japonsko), S. KURODA (392 Japonsko), K. OHYA (392 Japonsko), Sonia BARTÁKOVÁ (203 Česká republika, garant, domácí), H. AOKI (392 Japonsko) a Shohei KASUGAI (392 Japonsko)

Vydání

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, Japan, 2011, 0957-4530

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30200 3.2 Clinical medicine

Stát vydavatele

Japonsko

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 2.316

Kód RIV

RIV/00216224:14110/11:00054875

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1007/s10856-011-4329-0

UT WoS

000291702500013

Klíčová slova česky

implantát; povlakování; hydroxyapatite

Klíčová slova anglicky

implant; coating; hydroxyapatite

Příznaky

Mezinárodní význam

Změněno: 11. 4. 2012 14:27, Mgr. Michal Petr

Anotace

V originále

A sputtering technique followed by a low temperature hydrothermal treatment has been demonstrated to produce a dense-and-bioactive hydroxyapatite thin film coating. The purpose of the present study was to investigate osteoblast and osteoclast responses to the hydroxyapatite coated plates and titanium plates with similar roughness. Rat bone marrow stromal cells were cultured on these plates to induce osteoblasts. The cells showed a significantly enhanced proliferation on the hydroxyapatite surface, accompanied by increase of osteoblastic phenotypes. The co-cultured osteoclasts exhibited the significantly different cell number and morphology between the hydroxyapatite and the titanium surfaces. A series of osteoclast marker genes were more stimulated on the hydroxyapatite and thirty two percent of the hydroxyapatite surface area could be resorbed by osteoclasts. The thin film sputtered hydroxyapatite could provide a favorable surface for both osteoblast and osteoclast formation and their function, indicating its good osteoconductivity and biodegradability.

Návaznosti

1M0528, projekt VaV

Název: Stomatologické výzkumné centrum

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Stomatologické výzkumné centrum

Citovat

HAO, J., S. KURODA, K. OHYA, Sonia BARTÁKOVÁ, H. AOKI a Shohei KASUGAI. Enhanced osteoblast and osteoclast responses to a thin film sputtered hydroxyapatite coating. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE. Japan, 2011, roč. 22, č. 6, s. 1489-1499. ISSN 0957-4530. Dostupné z: https://dx.doi.org/10.1007/s10856-011-4329-0.

@article{965969,
   author = {Hao, J. and Kuroda, S. and Ohya, K. and Bartáková, Sonia and Aoki, H. and Kasugai, Shohei},
   article_location = {Japan},
   article_number = {6},
   doi = {http://dx.doi.org/10.1007/s10856-011-4329-0},
   keywords = {implant; coating; hydroxyapatite},
   language = {eng},
   issn = {0957-4530},
   journal = {JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE},
   title = {Enhanced osteoblast and osteoclast responses to a thin film sputtered hydroxyapatite coating},
   volume = {22},
   year = {2011}
}

TY  - JOUR
ID  - 965969
AU  - Hao, J. - Kuroda, S. - Ohya, K. - Bartáková, Sonia - Aoki, H. - Kasugai, Shohei
PY  - 2011
TI  - Enhanced osteoblast and osteoclast responses to a thin film sputtered hydroxyapatite coating
JF  - JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
VL  - 22
IS  - 6
SP  - 1489-1499
EP  - 1489-1499
SN  - 09574530
KW  - implant
KW  - coating
KW  - hydroxyapatite
N2  - A sputtering technique followed by a low temperature hydrothermal treatment has been demonstrated to produce a dense-and-bioactive hydroxyapatite thin film coating. The purpose of the present study was to investigate osteoblast and osteoclast responses to the hydroxyapatite coated plates and titanium plates with similar roughness. Rat bone marrow stromal cells were cultured on these plates to induce osteoblasts. The cells showed a significantly enhanced proliferation on the hydroxyapatite surface, accompanied by increase of osteoblastic phenotypes. The co-cultured osteoclasts exhibited the significantly different cell number and morphology between the hydroxyapatite and the titanium surfaces. A series of osteoclast marker genes were more stimulated on the hydroxyapatite and thirty two percent of the hydroxyapatite surface area could be resorbed by osteoclasts. The thin film sputtered hydroxyapatite could provide a favorable surface for both osteoblast and osteoclast formation and their function, indicating its good osteoconductivity and biodegradability.
ER  -

HAO, J., S. KURODA, K. OHYA, Sonia BARTÁKOVÁ, H. AOKI a Shohei KASUGAI. Enhanced osteoblast and osteoclast responses to a thin film sputtered hydroxyapatite coating. \textit{JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE}. Japan, 2011, roč.~22, č.~6, s.~1489-1499. ISSN~0957-4530. Dostupné z: https://dx.doi.org/10.1007/s10856-011-4329-0.

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