LENZ, Jiří, Petr KARÁSEK, Jiří JARKOVSKÝ, Katarína MÚČKOVÁ, Petr DÍTĚ, Zdeněk KALA, Renata VESELSKÁ and Markéta HERMANOVÁ. Clinicopathological correlations of nestin expression in surgically resectable pancreatic cancer including an analysis of perineural invasion. Journal of Gastrointestinal and Liver Diseases. 2011, vol. 20, No 4, p. 389-396. ISSN 1841-8724.
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Basic information
Original name Clinicopathological correlations of nestin expression in surgically resectable pancreatic cancer including an analysis of perineural invasion
Authors LENZ, Jiří (203 Czech Republic, belonging to the institution), Petr KARÁSEK (203 Czech Republic, belonging to the institution), Jiří JARKOVSKÝ (203 Czech Republic, belonging to the institution), Katarína MÚČKOVÁ (703 Slovakia, belonging to the institution), Petr DÍTĚ (203 Czech Republic, belonging to the institution), Zdeněk KALA (203 Czech Republic, belonging to the institution), Renata VESELSKÁ (203 Czech Republic, belonging to the institution) and Markéta HERMANOVÁ (203 Czech Republic, guarantor, belonging to the institution).
Edition Journal of Gastrointestinal and Liver Diseases, 2011, 1841-8724.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30000 3. Medical and Health Sciences
Country of publisher Romania
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 1.811
RIV identification code RIV/00216224:14110/11:00054986
Organization unit Faculty of Medicine
UT WoS 000298315500012
Keywords in English Pancreatic cancer; nestin; prognostic factor; perineural invasion.
Tags International impact, Reviewed
Changed by Changed by: prof. MUDr. Markéta Hermanová, Ph.D., učo 1598. Changed: 8/8/2012 17:00.
Abstract
An intimate link of nestin to biological process of pancreatic cancer was confirmated. The expression of nestin did not prove to be valuable prognostic factor and an immunohistochemical assesment of nestin expression is not superior to conventional prognostic factors in PDAC. A correlation between nestin expression in tumor cells and PNI was not confirmed and expression of nestin in nerve fibres of both PDAC and CP tissues seems to reflect the process of neural remodeling responsible for pancreatic neuropathy.
Links
MSM0021622415, plan (intention)Name: Molekulární podstata buněčných a tkáňových regulací
Investor: Ministry of Education, Youth and Sports of the CR, Molecular basis of cell and tissue regulations
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