a 2010

FREQUENCY OF THE SPECTRAL PEAK IN THE RANGE OF FREQUENCIES BETWEEN 60 AND 120 mHz IN CROSSSPECTRA OF BLOOD PRESSURE AND HEART RATE FLUCTUATION IN YOUNG DIABETICS

HONZÍKOVÁ, Nataša, Michal JAVORKA, Ingrid TONHAJZEROVÁ, Kamil JAVORKA, Antonín KRTIČKA et. al.

Základní údaje

Originální název

FREQUENCY OF THE SPECTRAL PEAK IN THE RANGE OF FREQUENCIES BETWEEN 60 AND 120 mHz IN CROSSSPECTRA OF BLOOD PRESSURE AND HEART RATE FLUCTUATION IN YOUNG DIABETICS

Autoři

HONZÍKOVÁ, Nataša (203 Česká republika, garant, domácí), Michal JAVORKA (703 Slovensko), Ingrid TONHAJZEROVÁ (703 Slovensko), Kamil JAVORKA (703 Slovensko), Antonín KRTIČKA (203 Česká republika) a Bohumil FIŠER (203 Česká republika, domácí)

Vydání

Physiological Research : Proceedings of the Czech and Slovak Physiological Societies, 2010

Další údaje

Jazyk

angličtina

Typ výsledku

Konferenční abstrakt

Obor

30105 Physiology

Stát vydavatele

Kanada

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 1.646

Kód RIV

RIV/00216224:14110/10:00055008

Organizační jednotka

Lékařská fakulta

ISSN

Klíčová slova anglicky

baroreflex sensitivity; cross-spectra ;diabetes mellitus; ow-spectrum peak frequency; adolescents

Příznaky

Mezinárodní význam
Změněno: 18. 1. 2012 11:38, Mgr. Michal Petr

Anotace

V originále

The relatively well-preserved baroreflex sensitivity (BRS) in young diabetics is accompanied by an increased time delay within the baroreflex loop and a decrease in the synchronisation level between blood pressure and heart rate fluctuations. The aim of the present study was the determination of the frequency of the spectral peak (f) in crossspectra of systolic blood pressure and heart rate fluctuations (frequency range between 60 and 120 mHz) and BRS by the spectral method in young diabetics and matched healthy controls. We investigated 14 type- 1 diabetics (age 20-25 years, diabetes duration 10-15 years) and 14 agematched controls. Blood pressure and heart rate were recorded beat-tobeat by Finapres for 40 minutes. BRS was determined by the spectral method, f was measured in the cross-spectra of systolic blood pressure and heart rate fluctuations. Mean BRS was 14.58 ms/mmHg in controls and 10.31 ms/mmHg in diabetics. The difference was statistically insignificant (p=0.06). Mean f was 93.70 mHz in controls and 88.79 mHz in diabetics; the difference was significant. It is concluded that the frequency of the spectral peak in the cross-spectra of systolic blood pressure and heart rate fluctuations in the range between 60 and 120 mHz is decreased in young diabetics and provides a diagnostic tool for the detection of autonomic nervous system impairment in these patients.

Návaznosti

MSM0021622402, záměr
Název: Časná diagnostika a léčba kardiovaskulárních chorob
Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Časná diagnostika a léčba kardiovaskulárních chorob