Other formats:
BibTeX
LaTeX
RIS
@article{967941,
author = {Zedek, František and Bureš, Petr},
article_location = {San Francisco},
article_number = {1},
doi = {http://dx.doi.org/10.1371/journal.pone.0030496},
keywords = {centromerický tah; holocentrické chromosomy; kinetochorové proteiny; telokinetická meiosa},
language = {eng},
issn = {1932-6203},
journal = {PloS ONE},
title = {Evidence for Centromere Drive in the Holocentric Chromosomes of Caenorhabditis},
url = {http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0030496},
volume = {7},
year = {2012}
}
TY - JOUR
ID - 967941
AU - Zedek, František - Bureš, Petr
PY - 2012
TI - Evidence for Centromere Drive in the Holocentric Chromosomes of Caenorhabditis
JF - PloS ONE
VL - 7
IS - 1
SP - 1-5
EP - 1-5
PB - Public Library of Science
SN - 19326203
KW - centromerický tah
KW - holocentrické chromosomy
KW - kinetochorové proteiny
KW - telokinetická meiosa
UR - http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0030496
N2 - In monocentric organisms with asymmetric meiosis, the kinetochore proteins, such as CENH3 and CENP-C, evolve adaptively to counterbalance the deleterious effects of centromere drive, which is caused by the expansion of centromeric satellite repeats. The selection regimes that act on CENH3 and CENP-C genes have not been analyzed in organisms with holocentric chromosomes, although holocentrism is speculated to have evolved to suppress centromere drive. We tested both CENH3 and CENP-C for positive selection in several species of the holocentric genus Caenorhabditis using the maximum likelihood approach and sliding-window analysis. Although CENP-C did not show any signs of positive selection, positive selection has been detected in the case of CENH3. These results support the hypothesis that centromere drive occurs in Nematoda, at least in the telokinetic meiosis of Caenorhabditis.
ER -
ZEDEK, František and Petr BUREŠ. Evidence for Centromere Drive in the Holocentric Chromosomes of Caenorhabditis. \textit{PloS ONE}. San Francisco: Public Library of Science, 2012, vol.~7, No~1, p.~1-5. ISSN~1932-6203. Available from: https://dx.doi.org/10.1371/journal.pone.0030496.
|
