FIEDLER, Jiří, Vladimír PŘIBÁŇ, Ondřej ŠKODA, Ivo SCHENK, Věra SCHENKOVÁ a Simona POLÁKOVÁ. Cognitive outcome after EC-IC bypass surgery in hemodynamic cerebral ischemia. Acta Neurichirurgica. Wien: Springer, 2011, roč. 153, č. 6, s. 1303-1312. ISSN 0001-6268. Dostupné z: https://dx.doi.org/10.1007/s00701-011-0949-x.
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Základní údaje
Originální název Cognitive outcome after EC-IC bypass surgery in hemodynamic cerebral ischemia
Autoři FIEDLER, Jiří (203 Česká republika, garant, domácí), Vladimír PŘIBÁŇ (203 Česká republika, domácí), Ondřej ŠKODA (203 Česká republika), Ivo SCHENK (203 Česká republika), Věra SCHENKOVÁ (203 Česká republika) a Simona POLÁKOVÁ (203 Česká republika).
Vydání Acta Neurichirurgica, Wien, Springer, 2011, 0001-6268.
Další údaje
Originální jazyk angličtina
Typ výsledku Článek v odborném periodiku
Obor 30000 3. Medical and Health Sciences
Stát vydavatele Rakousko
Utajení není předmětem státního či obchodního tajemství
Impakt faktor Impact factor: 1.520
Kód RIV RIV/00216224:14110/11:00081790
Organizační jednotka Lékařská fakulta
Doi http://dx.doi.org/10.1007/s00701-011-0949-x
UT WoS 000290795700021
Klíčová slova anglicky Carotid arteries; Cerebral revascularization; Cognition; Brain ischemia; EC-IC bypass
Příznaky Mezinárodní význam, Recenzováno
Změnil Změnila: Ing. Mgr. Věra Pospíšilíková, učo 9005. Změněno: 20. 10. 2015 10:20.
Anotace
Objective The purpose of this study was to evaluate cognitive functions in patients undergoing extracranial-intracranial (EC-IC) bypass surgery for cerebral ischemia. Population and methods From August 2003 to January 2009, 276 patients with occluded internal carotid arteries (ICA) were screened. Forty of these met the criteria for a low-flow EC-IC bypass. These patients were identified based on evidence of exhausted vasomotor reactivity (VMR) using the Doppler CO(2) test and CT perfusion. These patients were invited to have a complete battery of neuropsychological tests preoperatively and 12 months after surgery. Complete neurocognitive testing was finished in 20 patients. Results This group of 20 patients showed preoperative cognitive impairment ranging from mild to medium-severe. There were no cases of stroke ipsilateral to the operated side during the follow-up period. VMR improvement was seen in all patients within 6 months of surgery. A comparison using a paired t-test demonstrated significant improvement 12 months after surgery in the following neuropsychological tests: WAIS-R (p = 0.01), Number Collection Test (p = 0.02), Trail Making Test (p = 0.03), and Benton Visual Retention Test (p = 0.05). Repeat analysis of variance (ANOVA) suggested the following predictors associated with cognitive improvement:the presence of ophthalmic collateral flow (p = 0.04), preoperative amaurosis fugax (p = 0.02), and external watershed infarction detected by MRI (p = 0.04). Conclusion Patients with occlusion of the ICA and exhausted VMR have cognitive impairment prior to EC-IC bypass surgery. Twelve months after surgery, there is significant improvement in various areas of cognition.
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