2011
The creation and progress of the J Project in Eastern and Central Europe
MARÓDI, LászlóZákladní údaje
Originální název
The creation and progress of the J Project in Eastern and Central Europe
Autoři
MARÓDI, László
Vydání
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 2011, 0077-8923
Další údaje
Jazyk
angličtina
Typ výsledku
Článek v odborném periodiku
Obor
30300 3.3 Health sciences
Stát vydavatele
Spojené státy
Utajení
není předmětem státního či obchodního tajemství
Impakt faktor
Impact factor: 3.155
Organizační jednotka
Lékařská fakulta
UT WoS
000299397400008
Klíčová slova anglicky
primary immunodeficiency; network; genetic technologies; socioeconomic conditions
Příznaky
Mezinárodní význam
Změněno: 13. 4. 2012 11:14, Mgr. Michal Petr
Anotace
V originále
Primary immunodeficiencies (PIDs)havenowbecomerecognized as aworldwide health problem. Rapid development of immunological and genetic technologies has led to the discovery of more than 200 PIDs andmore than 150 diseaserelated genes. Progress in the field is expected to take a new turn after the introduction of new-generation sequencing technologies that will enable searches for currently unknown PID-related genes. By contrast, even with progress in molecular genetics, many patients remain ill and die early because of the lack of diagnostic or treatment facilities, or both. Thus, the gap between the knowledge accumulated and the appropriate management of patients with PIDs in everyday clinical practice has widened, necessitating PID awareness, particularly in countries with poor socioeconomic conditions. The J Project, established as a physician education and research collaboration program in Eastern and Central Europe, demonstrates how professional responsibility and long-term joint efforts can make a beneficial difference for patients with inborn errors of immunity.