SLABÝ, Ondřej, Petra FALTEJSKOVÁ, Marek SVOBODA, Renata HÉŽOVÁ, Lenka RADOVÁ, Jiří ŠÁNA and Rostislav VYZULA. Detection of metastatic spread to lymph nodes in primary tumors of colorectal cancer patients by analysis of microRNA expression profiles. In The 16th Annual Meeting of the RNA Society and The 13th Annual Meeting of the RNA Society of Japan, RNA 2011, Kyoto, Japan. 2011.
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Basic information
Original name Detection of metastatic spread to lymph nodes in primary tumors of colorectal cancer patients by analysis of microRNA expression profiles.
Authors SLABÝ, Ondřej, Petra FALTEJSKOVÁ, Marek SVOBODA, Renata HÉŽOVÁ, Lenka RADOVÁ, Jiří ŠÁNA and Rostislav VYZULA.
Edition The 16th Annual Meeting of the RNA Society and The 13th Annual Meeting of the RNA Society of Japan, RNA 2011, Kyoto, Japan, 2011.
Other information
Original language English
Type of outcome Conference abstract
Field of Study 30200 3.2 Clinical medicine
Country of publisher Japan
Confidentiality degree is not subject to a state or trade secret
WWW URL
Organization unit Masaryk Memorial Cancer Institute
Keywords (in Czech) mikroRNA; kolorektální karcinom; RLU
Keywords in English microRNA; colorectal cancer; RLN
Tags International impact
Changed by Changed by: Mgr. Michal Petr, učo 65024. Changed: 18/4/2012 11:26.
Abstract
The aim of this study was molecular characterization of primary tumors of colon and rectum using modern and progressive analysis based on expression profiles of 667 microRNAs by quantitative real-time PCR arrays. We analyzed expression profiles of 20 patients without lymph node positivity and 25 patients with lymph node positivity to identify miRNA differentially expressed between these two groups that would alow us to diagnose presence of lymph nodes metastases directly from the primary tumor.
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