Instrumental activities of daily living in Parkinson's disease
dementia as compared with Alzheimer's disease: Relationship to
motor disability and cognitive deficits: A pilot study

J 2011

Instrumental activities of daily living in Parkinson's disease dementia as compared with Alzheimer's disease: Relationship to motor disability and cognitive deficits: A pilot study

RAŠOVSKÁ, Hana a Irena REKTOROVÁ

Základní údaje

Originální název

Instrumental activities of daily living in Parkinson's disease dementia as compared with Alzheimer's disease: Relationship to motor disability and cognitive deficits: A pilot study

Autoři

RAŠOVSKÁ, Hana (203 Česká republika, garant, domácí) a Irena REKTOROVÁ (203 Česká republika, domácí)

Vydání

Journal of the Neurological Sciences, 2011, 0022-510X

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30000 3. Medical and Health Sciences

Stát vydavatele

Nizozemské království

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 2.353

Kód RIV

RIV/00216224:14110/11:00055892

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1016/j.jns.2011.07.048

UT WoS

000296927500061

Klíčová slova anglicky

Parkinsons disease dementia; Alzheimers disease; Instrumental activities of daily living; Extrapyramidal symptoms; Cognitive functions

Příznaky

Mezinárodní význam

Změněno: 1. 3. 2012 11:47, Mgr. Michal Petr

Anotace

V originále

Our objective was to assess which clinical factors contribute most to the impairment of instrumental activities of daily living (IADL) in patients with dementia in Parkinsons disease (PDD) as compared to age- and dementia duration-matched patients with Alzheimer's disease (AD). Methods: Eighteen consecutive subjects (16 men, 2 women) with PDD and 30 age- and dementia duration-matched subjects with AD (13 men, 17 women) were recruited. The groups were not matched for their Mini-Mental Status Examination (MMSE) score. Neuropsychiatric, cognitive and motor data were collected in a routine clinical setting using the MMSE, four brief tests of the seven minute screen (i.e. the Benton Temporal Orientation, Grober and Buschkes enhanced cued recall, verbal fluency, and the clock drawing test), the Neuropsychiatric Inventory, a modified version of the Hoehn and Yahr scale and a Czech modified version of Lawton's IADL questionnaire. The IADL scores were correlated with clinical variables in each group. Results: There were no differences in IADL abilities between both groups. A significant association was found between IADL and cognitive impairment as measured by screening tests in the AD group. In the PDD group, IADL scores were particularly correlated with PD duration (r = -0.73, p<0.01) and the Hoehn and Yahr score (r = -0.59, p<0.01). Conclusion: Our pilot study results show that motor deficits remain the major contributor to IADL impairment in PDD.

Návaznosti

MSM0021622404, záměr

Název: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS

Citovat

RAŠOVSKÁ, Hana a Irena REKTOROVÁ. Instrumental activities of daily living in Parkinson's disease dementia as compared with Alzheimer's disease: Relationship to motor disability and cognitive deficits: A pilot study. Journal of the Neurological Sciences. 2011, roč. 310, 1-2, s. 279–282. ISSN 0022-510X. Dostupné z: https://dx.doi.org/10.1016/j.jns.2011.07.048.

@article{973678,
   author = {Rašovská, Hana and Rektorová, Irena},
   article_number = {1-2},
   doi = {http://dx.doi.org/10.1016/j.jns.2011.07.048},
   keywords = {Parkinsons disease dementia; Alzheimers disease; Instrumental activities of daily living; Extrapyramidal symptoms; Cognitive functions},
   language = {eng},
   issn = {0022-510X},
   journal = {Journal of the Neurological Sciences},
   note = {7th International Congress on Mental Dysfunction and other Non-Motor Features in Parkinsons Disease and Related Disorders, Barcelona, SPAIN, DEC 09-12, 2010},
   title = {Instrumental activities of daily living in Parkinson's disease dementia as compared with Alzheimer's disease: Relationship to motor disability and cognitive deficits: A pilot study},
   volume = {310},
   year = {2011}
}

TY  - JOUR
ID  - 973678
AU  - Rašovská, Hana - Rektorová, Irena
PY  - 2011
TI  - Instrumental activities of daily living in Parkinson's disease dementia as compared with Alzheimer's disease: Relationship to motor disability and cognitive deficits: A pilot study
JF  - Journal of the Neurological Sciences
VL  - 310
IS  - 1-2
SP  - 279–282
EP  - 279–282
SN  - 0022510X
N1  - 7th International Congress on Mental Dysfunction and other Non-Motor Features in Parkinsons Disease and Related Disorders, Barcelona, SPAIN, DEC 09-12, 2010
KW  - Parkinsons disease dementia
KW  - Alzheimers disease
KW  - Instrumental activities of daily living
KW  - Extrapyramidal symptoms
KW  - Cognitive functions
N2  - Our objective was to assess which clinical factors contribute most to the impairment of instrumental activities of daily living (IADL) in patients with dementia in Parkinsons disease (PDD) as compared to age- and dementia duration-matched patients with Alzheimer's disease (AD). Methods: Eighteen consecutive subjects (16 men, 2 women) with PDD and 30 age- and dementia duration-matched subjects with AD (13 men, 17 women) were recruited. The groups were not matched for their Mini-Mental Status Examination (MMSE) score. Neuropsychiatric, cognitive and motor data were collected in a routine clinical setting using the MMSE, four brief tests of the seven minute screen (i.e. the Benton Temporal Orientation, Grober and Buschkes enhanced cued recall, verbal fluency, and the clock drawing test), the Neuropsychiatric Inventory, a modified version of the Hoehn and Yahr scale and a Czech modified version of Lawton's IADL questionnaire. The IADL scores were correlated with clinical variables in each group. Results: There were no differences in IADL abilities between both groups. A significant association was found between IADL and cognitive impairment as measured by screening tests in the AD group. In the PDD group, IADL scores were particularly correlated with PD duration (r = -0.73, p<0.01) and the Hoehn and Yahr score (r = -0.59, p<0.01). Conclusion: Our pilot study results show that motor deficits remain the major contributor to IADL impairment in PDD.
ER  -

RAŠOVSKÁ, Hana a Irena REKTOROVÁ. Instrumental activities of daily living in Parkinson's disease dementia as compared with Alzheimer's disease: Relationship to motor disability and cognitive deficits: A pilot study. \textit{Journal of the Neurological Sciences}. 2011, roč.~310, 1-2, s.~279–282. ISSN~0022-510X. Dostupné z: https://dx.doi.org/10.1016/j.jns.2011.07.048.

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