Estrogenic activity in extracts and exudates of cyanobacteria
and green algae.

J 2012

Estrogenic activity in extracts and exudates of cyanobacteria and green algae.

SYCHROVÁ, Eliška, Tereza ŠTĚPÁNKOVÁ, Kateřina NOVÁKOVÁ, Luděk BLÁHA, J. P. GIESY et. al.

Základní údaje

Originální název

Estrogenic activity in extracts and exudates of cyanobacteria and green algae.

Autoři

SYCHROVÁ, Eliška (203 Česká republika, domácí), Tereza ŠTĚPÁNKOVÁ (203 Česká republika, domácí), Kateřina NOVÁKOVÁ (203 Česká republika, domácí), Luděk BLÁHA (203 Česká republika, domácí), J. P. GIESY (124 Kanada) a Klára HILSCHEROVÁ (203 Česká republika, garant, domácí)

Vydání

Environment International, OXFORD, ENGLAND, PERGAMON-ELSEVIER SCIENCE LTD, 2012, 0160-4120

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10511 Environmental sciences

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 6.248

Kód RIV

RIV/00216224:14310/12:00057297

Organizační jednotka

Přírodovědecká fakulta

DOI

http://dx.doi.org/10.1016/j.envint.2011.10.004

UT WoS

000300129100018

Klíčová slova anglicky

Cyanobacteria; Eutrophication; Endocrine disruption; Estrogenicity; Algae; Phytoplankton

Štítky

AKR, rivok

Změněno: 10. 4. 2013 13:02, Ing. Andrea Mikešková

Anotace

V originále

Most exudates from cyanobacteria and algae were estrogenic with potencies expressed at 50% of the maximum response under control of the estrogen receptor ranging from 0.2 to 7.2 ng 17 beta-estradiol (E-2) equivalents (EEQ)/L. The greatest estrogenic potency was observed for common species Microcystis aerigunosa. Aqueous extracts of green algae and one species of cyanobacteria (Aphanizomenon gracile) elicited significant estrogenicity with EEQ ranging from 15 to 280 ng 17 beta-estradiol (E-2)/g dry weight. Scenedesmus quadricauda exudates and extracts of Aphanizomenon flos-aquae were antagonistic to the ER when coexposed to E2. The EEQ potency was not correlated with concentrations of cyanotoxins, such as microcystin and cylindrospermopsin, which suggests that the EEQ was comprised of other compounds. The study demonstrates some differences between the estrogenic potency of aqueous extracts prepared from the same species, but of different origin, while the effects of exudates were comparable within species.

Návaznosti

ED0001/01/01, projekt VaV

Název: CETOCOEN

GA524/08/0496, projekt VaV

Název: Mechanismy nádorové promoce metabolitů toxických sinic

Investor: Grantová agentura ČR, Mechanismy nádorové promoce metabolitů toxických sinic

2B08036, projekt VaV

Název: Nové molekulárně biologické a biochemické metody pro monitoring estrogenů a dalších chemických endokrinních disruptorů (Akronym: ENVISCREEN)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Nové molekulárně biologické a biochemické metody pro monitoring estrogenů a dalších chemických endokrinních disruptorů

Citovat

SYCHROVÁ, Eliška, Tereza ŠTĚPÁNKOVÁ, Kateřina NOVÁKOVÁ, Luděk BLÁHA, J. P. GIESY a Klára HILSCHEROVÁ. Estrogenic activity in extracts and exudates of cyanobacteria and green algae. Environment International. OXFORD, ENGLAND: PERGAMON-ELSEVIER SCIENCE LTD, 2012, roč. 39, č. 1, s. 134-140. ISSN 0160-4120. Dostupné z: https://dx.doi.org/10.1016/j.envint.2011.10.004.

@article{975203,
   author = {Sychrová, Eliška and Štěpánková, Tereza and Nováková, Kateřina and Bláha, Luděk and Giesy, J. P. and Hilscherová, Klára},
   article_location = {OXFORD, ENGLAND},
   article_number = {1},
   doi = {http://dx.doi.org/10.1016/j.envint.2011.10.004},
   keywords = {Cyanobacteria; Eutrophication; Endocrine disruption; Estrogenicity; Algae; Phytoplankton},
   language = {eng},
   issn = {0160-4120},
   journal = {Environment International},
   title = {Estrogenic activity in extracts and exudates of cyanobacteria and green algae.},
   volume = {39},
   year = {2012}
}

TY  - JOUR
ID  - 975203
AU  - Sychrová, Eliška - Štěpánková, Tereza - Nováková, Kateřina - Bláha, Luděk - Giesy, J. P. - Hilscherová, Klára
PY  - 2012
TI  - Estrogenic activity in extracts and exudates of cyanobacteria and green algae.
JF  - Environment International
VL  - 39
IS  - 1
SP  - 134-140
EP  - 134-140
PB  - PERGAMON-ELSEVIER SCIENCE LTD
SN  - 01604120
KW  - Cyanobacteria
KW  - Eutrophication
KW  - Endocrine disruption
KW  - Estrogenicity
KW  - Algae
KW  - Phytoplankton
N2  - Most exudates from cyanobacteria and algae were estrogenic with potencies expressed at 50% of the maximum response under control of the estrogen receptor ranging from 0.2 to 7.2 ng 17 beta-estradiol (E-2) equivalents (EEQ)/L. The greatest estrogenic potency was observed for common species Microcystis aerigunosa. Aqueous extracts of green algae and one species of cyanobacteria (Aphanizomenon gracile) elicited significant estrogenicity with EEQ ranging from 15 to 280 ng 17 beta-estradiol (E-2)/g dry weight. Scenedesmus quadricauda exudates and extracts of Aphanizomenon flos-aquae were antagonistic to the ER when coexposed to E2. The EEQ potency was not correlated with concentrations of cyanotoxins, such as microcystin and cylindrospermopsin, which suggests that the EEQ was comprised of other compounds. The study demonstrates some differences between the estrogenic potency of aqueous extracts prepared from the same species, but of different origin, while the effects of exudates were comparable within species.
ER  -

SYCHROVÁ, Eliška, Tereza ŠTĚPÁNKOVÁ, Kateřina NOVÁKOVÁ, Luděk BLÁHA, J. P. GIESY a Klára HILSCHEROVÁ. Estrogenic activity in extracts and exudates of cyanobacteria and green algae. \textit{Environment International}. OXFORD, ENGLAND: PERGAMON-ELSEVIER SCIENCE LTD, 2012, roč.~39, č.~1, s.~134-140. ISSN~0160-4120. Dostupné z: https://dx.doi.org/10.1016/j.envint.2011.10.004.

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