| FALTEJSKOVÁ, Petra, Andrej BEŠŠE, Sabina ŠEVČÍKOVÁ, Lenka KUBICZKOVÁ, Marek SVOBODA, Jan ŠMARDA, Igor KISS, Rostislav VYZULA and Ondřej SLABÝ. Clinical correlations of miR-21 expression in colorectal cancer patients and effects of its inhibition on DLD1 colon cancer cells. International Journal of Colorectal Disease. New York: Springer, 2012, vol. 27, No 11, p. 1401-1408. ISSN 0179-1958. Available from: https://dx.doi.org/10.1007/s00384-012-1461-3. |
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@article{979090,
author = {Faltejsková, Petra and Bešše, Andrej and Ševčíková, Sabina and Kubiczková, Lenka and Svoboda, Marek and Šmarda, Jan and Kiss, Igor and Vyzula, Rostislav and Slabý, Ondřej},
article_location = {New York},
article_number = {11},
doi = {http://dx.doi.org/10.1007/s00384-012-1461-3},
keywords = {miR-21; colorectal cancer; DLD-1; 5-FU; SN38; L-OHP; sensitivity; apoptosis; migration},
language = {eng},
issn = {0179-1958},
journal = {International Journal of Colorectal Disease},
title = {Clinical correlations of miR-21 expression in colorectal cancer patients and effects of its inhibition on DLD1 colon cancer cells},
url = {http://link.springer.com/article/10.1007%2Fs00384-012-1461-3},
volume = {27},
year = {2012}
}
TY - JOUR
ID - 979090
AU - Faltejsková, Petra - Bešše, Andrej - Ševčíková, Sabina - Kubiczková, Lenka - Svoboda, Marek - Šmarda, Jan - Kiss, Igor - Vyzula, Rostislav - Slabý, Ondřej
PY - 2012
TI - Clinical correlations of miR-21 expression in colorectal cancer patients and effects of its inhibition on DLD1 colon cancer cells
JF - International Journal of Colorectal Disease
VL - 27
IS - 11
SP - 1401-1408
EP - 1401-1408
PB - Springer
SN - 01791958
KW - miR-21
KW - colorectal cancer
KW - DLD-1
KW - 5-FU
KW - SN38
KW - L-OHP
KW - sensitivity
KW - apoptosis
KW - migration
UR - http://link.springer.com/article/10.1007%2Fs00384-012-1461-3
L2 - http://link.springer.com/article/10.1007%2Fs00384-012-1461-3
N2 - MicroRNA-21 (miR-21) is one of the miRNAs that are frequently and highly overexpressed in tumor tissue of colorectal cancer patients. We confirmed over-expression of miR-21 in colorectal cancer patients and its correlation with advanced disease and shorter overall survival. Our results suggest that it is increased migration activity of colon cancer cells over-expressing miR-21 that can be responsible for these effects.
ER -
FALTEJSKOVÁ, Petra, Andrej BEŠŠE, Sabina ŠEVČÍKOVÁ, Lenka KUBICZKOVÁ, Marek SVOBODA, Jan ŠMARDA, Igor KISS, Rostislav VYZULA and Ondřej SLABÝ. Clinical correlations of miR-21 expression in colorectal cancer patients and effects of its inhibition on DLD1 colon cancer cells. \textit{International Journal of Colorectal Disease}. New York: Springer, 2012, vol.~27, No~11, p.~1401-1408. ISSN~0179-1958. Available from: https://dx.doi.org/10.1007/s00384-012-1461-3.
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