SVOBODA, Marek, Jiří ŠÁNA, Martina RÉDOVÁ, Jiří NAVRÁTIL, Markéta PALÁCOVÁ, Pavel FABIAN, Ondřej SLABÝ and Rostislav VYZULA. MiR-34b is associated with clinical outcome in triple-negative breast cancer patients. Diagnostic Pathology. 2012, vol. 7, March, p. 31-35. ISSN 1746-1596. Available from: https://dx.doi.org/10.1186/1746-1596-7-31.
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Basic information
Original name MiR-34b is associated with clinical outcome in triple-negative breast cancer patients.
Authors SVOBODA, Marek, Jiří ŠÁNA, Martina RÉDOVÁ, Jiří NAVRÁTIL, Markéta PALÁCOVÁ, Pavel FABIAN, Ondřej SLABÝ and Rostislav VYZULA.
Edition Diagnostic Pathology, 2012, 1746-1596.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30200 3.2 Clinical medicine
Country of publisher United Kingdom of Great Britain and Northern Ireland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 1.850
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1186/1746-1596-7-31
UT WoS 000303885300001
Keywords in English triple-negative breast cancer; miR-34a; miR-34b; miR-34c; prognosis
Tags International impact, Reviewed
Changed by Changed by: Ing. Mgr. Věra Pospíšilíková, učo 9005. Changed: 15/10/2015 13:07.
Abstract
Breast cancer is the most common malignancy with the highest incidence rates among women worldwide. Triple-negative breast cancer (TNBC) represents the major phenotype of basal-like molecular subtype of breast cancer, characterized by higher incidence in young women and a very poor prognosis. MicroRNAs (miRNAs) are small non-coding RNAs playing significant role in the pathogenesis of many cancers including breast cancer. Therefore, miRNAs are also potential prognostic and/or predictive biomarkers in triple-negative breast cancer patients.
Links
NS10357, research and development projectName: Epidemiologické, genetické a klinicko-patologické aspekty ?triple-negativního? (ER-?, PR, c-ErbB2 negativního) karcinomu prsu v populaci českých žen.
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