MicroRNA in renal cell carcinoma – potential marker for
prediction of early metastasis after nephrectomy.

a 2011

MicroRNA in renal cell carcinoma – potential marker for prediction of early metastasis after nephrectomy.

RÉDOVÁ, Martina, Ondřej SLABÝ, Radek LAKOMÝ, Alexandr POPRACH, Jan HODEK et. al.

Základní údaje

Originální název

MicroRNA in renal cell carcinoma – potential marker for prediction of early metastasis after nephrectomy.

Autoři

RÉDOVÁ, Martina, Ondřej SLABÝ, Radek LAKOMÝ, Alexandr POPRACH, Jan HODEK, Marek SVOBODA, Lenka RADOVÁ, Pavel FABIAN, Robert ILIEV, Jaroslava OVESNÁ, Jaroslav MICHÁLEK a Rostislav VYZULA

Vydání

The Student Scientific Conference on Cancer Research, 2011

Další údaje

Jazyk

angličtina

Typ výsledku

Konferenční abstrakt

Obor

30200 3.2 Clinical medicine

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Organizační jednotka

Masarykův onkologický ústav

ISBN

978-80-210-5442-4

Klíčová slova anglicky

microRNA; renal cell carcinoma; metastasis; nephrectomy

Změněno: 7. 6. 2012 13:21, Mgr. Petra Vychytilová, Ph.D.

Anotace

V originále

Renal cell carcinoma (RCC) is the most common neoplasma of the adult kidney accounting for about 3 % of adult malignancies. RCC originates in the lining of the proximal renal tubule. The clear cell histology type, renal clear cell carcinoma (RCCC), is approximately 80-85%) of metastatic RCC and the most frequent subtype of RCC. Although surgigal resection remains the best curative therapy for RCC, after the curative nephrectomy, 20-40% patients will develope recurrence. Moreover, the absence of biomarkers for early detection and follow-up of the disease complicate the on-time diagnosis. For these reasons, it is worth revealing the underlying molecular and genetic mechanisms for RCC initiation and development, and finding new biomarkers which would enable prediction of early metastasis after curative nephrectomy.

Citovat

RÉDOVÁ, Martina, Ondřej SLABÝ, Radek LAKOMÝ, Alexandr POPRACH, Jan HODEK, Marek SVOBODA, Lenka RADOVÁ, Pavel FABIAN, Robert ILIEV, Jaroslava OVESNÁ, Jaroslav MICHÁLEK a Rostislav VYZULA. MicroRNA in renal cell carcinoma – potential marker for prediction of early metastasis after nephrectomy. In The Student Scientific Conference on Cancer Research. 2011. ISBN 978-80-210-5442-4.

@proceedings{984224,
   author = {Rédová, Martina and Slabý, Ondřej and Lakomý, Radek and Poprach, Alexandr and Hodek, Jan and Svoboda, Marek and Radová, Lenka and Fabian, Pavel and Iliev, Robert and Ovesná, Jaroslava and Michálek, Jaroslav and Vyzula, Rostislav},
   booktitle = {The Student Scientific Conference on Cancer Research},
   keywords = {microRNA; renal cell carcinoma; metastasis; nephrectomy},
   language = {eng},
   isbn = {978-80-210-5442-4},
   title = {MicroRNA in renal cell carcinoma – potential marker for prediction of early metastasis after nephrectomy.},
   year = {2011}
}

TY  - CONF
ID  - 984224
AU  - Rédová, Martina - Slabý, Ondřej - Lakomý, Radek - Poprach, Alexandr - Hodek, Jan - Svoboda, Marek - Radová, Lenka - Fabian, Pavel - Iliev, Robert - Ovesná, Jaroslava - Michálek, Jaroslav - Vyzula, Rostislav
PY  - 2011
TI  - MicroRNA in renal cell carcinoma – potential marker for prediction of early metastasis after nephrectomy.
SN  - 9788021054424
KW  - microRNA
KW  - renal cell carcinoma
KW  - metastasis
KW  - nephrectomy
N2  - Renal cell carcinoma (RCC) is the most common neoplasma of the adult kidney accounting for about 3 % of adult malignancies. RCC originates in the lining of the proximal renal tubule. The clear cell histology type, renal clear cell carcinoma (RCCC), is approximately 80-85%) of metastatic RCC and the most frequent subtype of RCC. Although surgigal resection remains the best curative therapy for RCC, after the curative nephrectomy, 20-40% patients will develope recurrence. Moreover, the absence of biomarkers for early detection and follow-up of the disease complicate the on-time diagnosis. For these reasons, it is worth revealing the underlying molecular and genetic mechanisms for RCC initiation and development, and finding new biomarkers which would enable prediction of early metastasis after curative nephrectomy.
ER  -

RÉDOVÁ, Martina, Ondřej SLABÝ, Radek LAKOMÝ, Alexandr POPRACH, Jan HODEK, Marek SVOBODA, Lenka RADOVÁ, Pavel FABIAN, Robert ILIEV, Jaroslava OVESNÁ, Jaroslav MICHÁLEK a Rostislav VYZULA. MicroRNA in renal cell carcinoma – potential marker for prediction of early metastasis after nephrectomy. In \textit{The Student Scientific Conference on Cancer Research}. 2011. ISBN~978-80-210-5442-4.

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