Expression Levels of Transcribed Ultraconserved Regions uc.73
and uc.388 Are Altered in Colorectal Cancer

J 2012

Expression Levels of Transcribed Ultraconserved Regions uc.73 and uc.388 Are Altered in Colorectal Cancer

ŠÁNA, Jiří, Simona HANKEOVÁ, Marek SVOBODA, Igor KISS, Rostislav VYZULA et. al.

Základní údaje

Originální název

Expression Levels of Transcribed Ultraconserved Regions uc.73 and uc.388 Are Altered in Colorectal Cancer

Autoři

ŠÁNA, Jiří (203 Česká republika, domácí), Simona HANKEOVÁ (203 Česká republika), Marek SVOBODA (203 Česká republika), Igor KISS (203 Česká republika), Rostislav VYZULA (203 Česká republika) a Ondřej SLABÝ (203 Česká republika, garant, domácí)

Vydání

Oncology, Basel, Karger, 2012, 0030-2414

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30200 3.2 Clinical medicine

Stát vydavatele

Švýcarsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 2.165

Kód RIV

RIV/00216224:14740/12:00060135

Organizační jednotka

Středoevropský technologický institut

DOI

http://dx.doi.org/10.1159/000336479

UT WoS

000301774000007

Klíčová slova anglicky

Colorectal cancer; Non-coding RNAs; Transcribed ultraconserved regions; uc.73; uc.388

Štítky

ok, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 10. 4. 2013 17:57, Olga Křížová

Anotace

V originále

The development of colorectal cancer (CRC) is characterized by multiple genetic alterations. Transcribed ultraconserved regions (T-UCRs) are a subset of 481 sequenc es longer than 200 bp, which are absolutely conserved between orthologous regions of human, rat and mouse genomes, and are actively transcribed. It has recently been proven in cancer systems that differentially expressed T-UCRs could alter the functional characteristics of malignant cells. Genome-wide profiling revealed that T-UCRs have distinct signatures in human leukemia and carcinoma.

Návaznosti

ED1.1.00/02.0068, projekt VaV

Název: CEITEC - central european institute of technology

Citovat

ŠÁNA, Jiří, Simona HANKEOVÁ, Marek SVOBODA, Igor KISS, Rostislav VYZULA a Ondřej SLABÝ. Expression Levels of Transcribed Ultraconserved Regions uc.73 and uc.388 Are Altered in Colorectal Cancer. Oncology. Basel: Karger, 2012, roč. 82, č. 2, s. 114-118. ISSN 0030-2414. Dostupné z: https://dx.doi.org/10.1159/000336479.

@article{984236,
   author = {Šána, Jiří and Hankeová, Simona and Svoboda, Marek and Kiss, Igor and Vyzula, Rostislav and Slabý, Ondřej},
   article_location = {Basel},
   article_number = {2},
   doi = {http://dx.doi.org/10.1159/000336479},
   keywords = {Colorectal cancer; Non-coding RNAs; Transcribed ultraconserved regions; uc.73; uc.388},
   language = {eng},
   issn = {0030-2414},
   journal = {Oncology},
   title = {Expression Levels of Transcribed Ultraconserved Regions uc.73 and uc.388 Are Altered in Colorectal Cancer},
   url = {http://www.karger.com/Article/Fulltext/336479},
   volume = {82},
   year = {2012}
}

TY  - JOUR
ID  - 984236
AU  - Šána, Jiří - Hankeová, Simona - Svoboda, Marek - Kiss, Igor - Vyzula, Rostislav - Slabý, Ondřej
PY  - 2012
TI  - Expression Levels of Transcribed Ultraconserved Regions uc.73 and uc.388 Are Altered in Colorectal Cancer
JF  - Oncology
VL  - 82
IS  - 2
SP  - 114-118
EP  - 114-118
PB  - Karger
SN  - 00302414
KW  - Colorectal cancer
KW  - Non-coding RNAs
KW  - Transcribed ultraconserved regions
KW  - uc.73
KW  - uc.388
UR  - http://www.karger.com/Article/Fulltext/336479
L2  - http://www.karger.com/Article/Fulltext/336479
N2  - The development of colorectal cancer (CRC) is characterized by multiple genetic alterations. Transcribed ultraconserved regions (T-UCRs) are a subset of 481 sequenc es longer than 200 bp, which are absolutely conserved between orthologous regions of human, rat and mouse genomes, and are actively transcribed. It has recently been proven in cancer systems that differentially expressed T-UCRs could alter the functional characteristics of malignant cells. Genome-wide profiling revealed that T-UCRs have distinct signatures in human leukemia and carcinoma.
ER  -

ŠÁNA, Jiří, Simona HANKEOVÁ, Marek SVOBODA, Igor KISS, Rostislav VYZULA a Ondřej SLABÝ. Expression Levels of Transcribed Ultraconserved Regions uc.73 and uc.388 Are Altered in Colorectal Cancer. \textit{Oncology}. Basel: Karger, 2012, roč.~82, č.~2, s.~114-118. ISSN~0030-2414. Dostupné z: https://dx.doi.org/10.1159/000336479.

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