2012
MicroRNAs and the Hallmarks of Cancer
SLABÝ, OndřejBasic information
Original name
MicroRNAs and the Hallmarks of Cancer
Authors
SLABÝ, Ondřej (203 Czech Republic, guarantor, belonging to the institution)
Edition
New York, MicroRNAs in Solid Cancer: From Biomarkers to Therapeutic Targets, p. 47-64, 18 pp. 2012
Publisher
Nova Science Publishers, Inc.
Other information
Language
English
Type of outcome
Chapter(s) of a specialized book
Field of Study
30200 3.2 Clinical medicine
Country of publisher
United States of America
Confidentiality degree
is not subject to a state or trade secret
Publication form
printed version "print"
RIV identification code
RIV/00216224:14740/12:00060175
Organization unit
Central European Institute of Technology
ISBN
978-1-61324-514-9
Keywords in English
microRNAs; cancer; hallmarks
Tags
International impact, Reviewed
Changed: 13/3/2013 13:35, Olga Křížová
Abstract
In the original language
A growing amount of evidences proves that microRNAs (miRNAs) can work as oncogenes (activating the malignant potential) or tumor suppressor genes (blocking the malignant potential) and they can affect all of the six hallmarks of cancer defined by Hanahan and Weinberg (2000) as: self-sufficiency in growth signals, insensitivity to growth inhibitory signals, evasion of apoptosis, limitless replicative potential, sustained angiogenesis and tissue invasion and metastasis. In this chapter we focus on miRNAs significance in these various aspects of cancer biology.
Links
| ED1.1.00/02.0068, research and development project |
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