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@inbook{987327,
author = {Thon, Vojtěch and Vlková, Marcela and Chovancová, Zita and Litzman, Jiří and Lokaj, Jindřich},
address = {Rijeka},
booktitle = {Clinical Flow Cytometry - Emerging Applications},
keywords = {Peripheral Blood; Diagnostics; Hypogammaglobulinaemia; Flow Based Enumeration},
howpublished = {elektronická verze "online"},
language = {eng},
location = {Rijeka},
isbn = {978-953-51-0575-6},
pages = {125-142},
publisher = {InTech},
title = {Flow Based Enumeration of Plasmablasts in Peripheral Blood After Vaccination as a Novel Diagnostic Marker for Assessing Antibody Responses in Patients with Hypogammaglobulinaemia},
url = {http://cdn.intechopen.com/pdfs/37060/InTechFlow_based_enumeration_of_plasmablasts_in_peripheral_blood_after_vaccination_as_a_novel_diagnostic_marker_for_assessing_antibody_responses_in_patients_with_hypogammaglobulinaemia.pdf},
year = {2012}
}
TY - CHAP
ID - 987327
AU - Thon, Vojtěch - Vlková, Marcela - Chovancová, Zita - Litzman, Jiří - Lokaj, Jindřich
PY - 2012
TI - Flow Based Enumeration of Plasmablasts in Peripheral Blood After Vaccination as a Novel Diagnostic Marker for Assessing Antibody Responses in Patients with Hypogammaglobulinaemia
VL - Biochemistry, Genetics and Molecular Biology
PB - InTech
CY - Rijeka
SN - 9789535105756
KW - Peripheral Blood
KW - Diagnostics
KW - Hypogammaglobulinaemia
KW - Flow Based Enumeration
UR - http://cdn.intechopen.com/pdfs/37060/InTechFlow_based_enumeration_of_plasmablasts_in_peripheral_blood_after_vaccination_as_a_novel_diagnostic_marker_for_assessing_antibody_responses_in_patients_with_hypogammaglobulinaemia.pdf
L2 - http://cdn.intechopen.com/pdfs/37060/InTechFlow_based_enumeration_of_plasmablasts_in_peripheral_blood_after_vaccination_as_a_novel_diagnostic_marker_for_assessing_antibody_responses_in_patients_with_hypogammaglobulinaemia.pdf
N2 - Hypogammaglobulinaemic patients are often started on immunoglobulin substitution therapy before antibody production is adequately evaluated. In such a situation, it is difficult to segregate transferred from antigen-induced specific antibody. Therefore we characterized changes in B-cell subpopulations in hypogammaglobulinaemic patients, including plasmablasts, in peripheral blood by flow cytometry after in vivo antigen challenge. We investigated the specificity of antibody production on the B-cell level by ELISPOT, which is independent of substitution therapy.
ER -
THON, Vojtěch, Marcela VLKOVÁ, Zita CHOVANCOVÁ, Jiří LITZMAN and Jindřich LOKAJ. Flow Based Enumeration of Plasmablasts in Peripheral Blood After Vaccination as a Novel Diagnostic Marker for Assessing Antibody Responses in Patients with Hypogammaglobulinaemia. Online. In \textit{Clinical Flow Cytometry - Emerging Applications}. Rijeka: InTech, 2012, p.~125-142. Biochemistry, Genetics and Molecular Biology. ISBN~978-953-51-0575-6.
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