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@inbook{987373,
author = {Bienertová Vašků, Julie and Bienert, Petr},
address = {New York},
booktitle = {Advances in Medicine and Biology : Volume 43},
keywords = {adipokines; fetal modelling; epigenetics},
howpublished = {tištěná verze "print"},
language = {eng},
location = {New York},
isbn = {978-1-62100-843-9},
pages = {263-272},
publisher = {Nova Science Publishers},
title = {Adipokines as an Important Factor Related to the Prenatal Programming of Nutritional Behaviour},
year = {2012}
}
TY - CHAP
ID - 987373
AU - Bienertová Vašků, Julie - Bienert, Petr
PY - 2012
TI - Adipokines as an Important Factor Related to the Prenatal Programming of Nutritional Behaviour
VL - Advances in Medicine and Biology
PB - Nova Science Publishers
CY - New York
SN - 9781621008439
KW - adipokines
KW - fetal modelling
KW - epigenetics
N2 - It has been suggested previously that some of the obesity-associated behavioral patterns as well as metabolic pathways are “programmed” during fetal development. The concept of “developmental metabolic programming” is based on the hypothesis that nutritional as well as metabolic status of the mother during the pregnancy affects the metabolism control in the child, thus resulting in a unique phenotype allowing for better adaptation of the infant to the environmental conditions. However, very little is known about factors that are responsible for this programming. The products of the white adipose tissue, so called adipokines, could be elegant candidates for controlling the process of fetal programming as they mostly correlated with the total fat mass and have pleiotropic effects both at parakrine and endocrine levels. It has been reported recently that e.g. leptin, adiponectin, resistin and visfatin as well as numerous other adipokines are associated with specific nutritional or metabolic conditions resulting in a wide range of adaptive phenotypes across the population. Moreover, placenta has been identified as a major source of adipokines, which also lead to the recognition of prenatal period as a highly specific, unique metabolic state resulting in specific feeding and metabolic patterns of the infant. This review covers the major aspects of adipokines in relation to prenatal fetal modelling of the nutritional behaviour.
ER -
BIENERTOVÁ VAŠKŮ, Julie a Petr BIENERT. Adipokines as an Important Factor Related to the Prenatal Programming of Nutritional Behaviour. In \textit{Advances in Medicine and Biology : Volume 43}. New York: Nova Science Publishers, 2012, s.~263-272. Advances in Medicine and Biology. ISBN~978-1-62100-843-9.
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