Adipokines as an Important Factor Related to the Prenatal Programming of Nutritional Behaviour

BIENERTOVÁ VAŠKŮ, Julie and Petr BIENERT. Adipokines as an Important Factor Related to the Prenatal Programming of Nutritional Behaviour. In Advances in Medicine and Biology : Volume 43. New York: Nova Science Publishers, 2012, p. 263-272. Advances in Medicine and Biology. ISBN 978-1-62100-843-9.

Basic information

• Original name: Adipokines as an Important Factor Related to the Prenatal Programming of Nutritional Behaviour
• Authors: BIENERTOVÁ VAŠKŮ, Julie (203 Czech Republic, guarantor, belonging to the institution) and Petr BIENERT (203 Czech Republic, belonging to the institution).
• Edition: New York, Advances in Medicine and Biology : Volume 43, p. 263-272, 10 pp. Advances in Medicine and Biology, 2012.
• Publisher: Nova Science Publishers

Other information

• Original language: English
• Type of outcome: Chapter(s) of a specialized book
• Field of Study: 30000 3. Medical and Health Sciences
• Country of publisher: United States of America
• Confidentiality degree: is not subject to a state or trade secret
• Publication form: printed version "print"
• RIV identification code: RIV/00216224:14110/12:00060426
• Organization unit: Faculty of Medicine
• ISBN: 978-1-62100-843-9
• Keywords in English: adipokines; fetal modelling; epigenetics

Abstract

It has been suggested previously that some of the obesity-associated behavioral patterns as well as metabolic pathways are “programmed” during fetal development. The concept of “developmental metabolic programming” is based on the hypothesis that nutritional as well as metabolic status of the mother during the pregnancy affects the metabolism control in the child, thus resulting in a unique phenotype allowing for better adaptation of the infant to the environmental conditions. However, very little is known about factors that are responsible for this programming. The products of the white adipose tissue, so called adipokines, could be elegant candidates for controlling the process of fetal programming as they mostly correlated with the total fat mass and have pleiotropic effects both at parakrine and endocrine levels. It has been reported recently that e.g. leptin, adiponectin, resistin and visfatin as well as numerous other adipokines are associated with specific nutritional or metabolic conditions resulting in a wide range of adaptive phenotypes across the population. Moreover, placenta has been identified as a major source of adipokines, which also lead to the recognition of prenatal period as a highly specific, unique metabolic state resulting in specific feeding and metabolic patterns of the infant. This review covers the major aspects of adipokines in relation to prenatal fetal modelling of the nutritional behaviour.

Abstract (in Czech)

Kapitola je přehledem úlohy jednotlivých adipokinů u fetálního modelování.