Towards a predictive model for post-stroke delirium

J 2012

Towards a predictive model for post-stroke delirium

KOŠŤÁLOVÁ, Milena, Josef BEDNAŘÍK, Adéla MITÁŠOVÁ, Ladislav DUŠEK, Radka MICHALČÁKOVÁ et. al.

Základní údaje

Originální název

Towards a predictive model for post-stroke delirium

Autoři

KOŠŤÁLOVÁ, Milena (203 Česká republika, garant, domácí), Josef BEDNAŘÍK (203 Česká republika, domácí), Adéla MITÁŠOVÁ (203 Česká republika, domácí), Ladislav DUŠEK (203 Česká republika, domácí), Radka MICHALČÁKOVÁ (203 Česká republika, domácí), Miloš KEŘKOVSKÝ (203 Česká republika, domácí), Tomáš KAŠPÁREK (203 Česká republika, domácí), Martina JEŽKOVÁ (203 Česká republika, domácí), Petra BALABÁNOVÁ (203 Česká republika, domácí) a Stanislav VOHÁŇKA (203 Česká republika, domácí)

Vydání

Brain Injury, London, Taylor & Francis, 2012, 0269-9052

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30000 3. Medical and Health Sciences

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 1.513

Kód RIV

RIV/00216224:14740/12:00060438

Organizační jednotka

Středoevropský technologický institut

DOI

http://dx.doi.org/10.3109/02699052.2012.660510

UT WoS

000305135100007

Klíčová slova anglicky

Delirium; stroke; risk factors; incidence; prediction

Štítky

ok, rivok

Příznaky

Mezinárodní význam

Změněno: 12. 4. 2013 13:32, Olga Křížová

Anotace

V originále

Primary objective: To assess predisposing and precipitating risk factors and create a predictive model for post-stroke delirium. Research design: A prospective observational study in a cohort of consecutive patients with ischemic stroke or intracerebral haematoma admitted within 24 hours of stroke onset. Methods: Patients were assessed daily for delirium during the first week by means of DSM-IV criteria and risk factors were recorded. Results: One hundred patients completed a 7-day evaluation (47 women and 53 men, median age 77 years). An episode of delirium was detected in 43 patients (43%). Using multivariate logistic regression, a predictive statistical model was developed that utilized independent risk factors: age (OR = 1.08; 95% CI = 1.02-1.15); intracerebral haemorrhage (OR = 6.11; 95% CI = 1.62-22.98), lesion volume > 40 ccm (OR = 3.99; 95% CI = 1.29-12.39) and either elevated gamma-glytamyl transferase (OR = 4.88; 95% CI = 1.45-16.35) and elevated serum bilirubin (OR = 3.70; 95% CI = 1.32-10.38) or maximum sequential organ failure assessment score >2 (OR = 3.33; 95% CI = 1.06-10.45) with acceptable sensitivity and specificity (69.0% and 80.7%). In ischemic strokes, total anterior circulation infarctions were more frequently associated with delirium (73.3% developed delirium) compared with the remainder of the groups combined (p = 0.004; OR = 6.66; 95% CI = 1.85-24.01). Conclusion: Higher age, metabolic disturbances, intracerebral haemorrhage and larger ischemic hemispheric strokes increase the risk of post-stroke delirium.

Návaznosti

MSM0021622404, záměr

Název: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS

NS10216, projekt VaV

Název: Diagnostika a patofyziologie deliria v intenzivní a pooperační péči

Investor: Ministerstvo zdravotnictví ČR, Diagnostika a patofyziologie v intenzivní a pooperační péči

Citovat

KOŠŤÁLOVÁ, Milena, Josef BEDNAŘÍK, Adéla MITÁŠOVÁ, Ladislav DUŠEK, Radka MICHALČÁKOVÁ, Miloš KEŘKOVSKÝ, Tomáš KAŠPÁREK, Martina JEŽKOVÁ, Petra BALABÁNOVÁ a Stanislav VOHÁŇKA. Towards a predictive model for post-stroke delirium. Brain Injury. London: Taylor & Francis, 2012, roč. 26, 7-8, s. 962-971. ISSN 0269-9052. Dostupné z: https://dx.doi.org/10.3109/02699052.2012.660510.

@article{987424,
   author = {Košťálová, Milena and Bednařík, Josef and Mitášová, Adéla and Dušek, Ladislav and Michalčáková, Radka and Keřkovský, Miloš and Kašpárek, Tomáš and Ježková, Martina and Balabánová, Petra and Voháňka, Stanislav},
   article_location = {London},
   article_number = {7-8},
   doi = {http://dx.doi.org/10.3109/02699052.2012.660510},
   keywords = {Delirium; stroke; risk factors; incidence; prediction},
   language = {eng},
   issn = {0269-9052},
   journal = {Brain Injury},
   title = {Towards a predictive model for post-stroke delirium},
   volume = {26},
   year = {2012}
}

TY  - JOUR
ID  - 987424
AU  - Košťálová, Milena - Bednařík, Josef - Mitášová, Adéla - Dušek, Ladislav - Michalčáková, Radka - Keřkovský, Miloš - Kašpárek, Tomáš - Ježková, Martina - Balabánová, Petra - Voháňka, Stanislav
PY  - 2012
TI  - Towards a predictive model for post-stroke delirium
JF  - Brain Injury
VL  - 26
IS  - 7-8
SP  - 962-971
EP  - 962-971
PB  - Taylor & Francis
SN  - 02699052
KW  - Delirium
KW  - stroke
KW  - risk factors
KW  - incidence
KW  - prediction
N2  - Primary objective: To assess predisposing and precipitating risk factors and create a predictive model for post-stroke delirium. Research design: A prospective observational study in a cohort of consecutive patients with ischemic stroke or intracerebral haematoma admitted within 24 hours of stroke onset. Methods: Patients were assessed daily for delirium during the first week by means of DSM-IV criteria and risk factors were recorded. Results: One hundred patients completed a 7-day evaluation (47 women and 53 men, median age 77 years). An episode of delirium was detected in 43 patients (43%). Using multivariate logistic regression, a predictive statistical model was developed that utilized independent risk factors: age (OR = 1.08; 95% CI = 1.02-1.15); intracerebral haemorrhage (OR = 6.11; 95% CI = 1.62-22.98), lesion volume > 40 ccm (OR = 3.99; 95% CI = 1.29-12.39) and either elevated gamma-glytamyl transferase (OR = 4.88; 95% CI = 1.45-16.35) and elevated serum bilirubin (OR = 3.70; 95% CI = 1.32-10.38) or maximum sequential organ failure assessment score >2 (OR = 3.33; 95% CI = 1.06-10.45) with acceptable sensitivity and specificity (69.0% and 80.7%). In ischemic strokes, total anterior circulation infarctions were more frequently associated with delirium (73.3% developed delirium) compared with the remainder of the groups combined (p = 0.004; OR = 6.66; 95% CI = 1.85-24.01). Conclusion: Higher age, metabolic disturbances, intracerebral haemorrhage and larger ischemic hemispheric strokes increase the risk of post-stroke delirium.
ER  -

KOŠŤÁLOVÁ, Milena, Josef BEDNAŘÍK, Adéla MITÁŠOVÁ, Ladislav DUŠEK, Radka MICHALČÁKOVÁ, Miloš KEŘKOVSKÝ, Tomáš KAŠPÁREK, Martina JEŽKOVÁ, Petra BALABÁNOVÁ a Stanislav VOHÁŇKA. Towards a predictive model for post-stroke delirium. \textit{Brain Injury}. London: Taylor \&{} Francis, 2012, roč.~26, 7-8, s.~962-971. ISSN~0269-9052. Dostupné z: https://dx.doi.org/10.3109/02699052.2012.660510.

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