Detailed Information on Publication Record
2012
B-cell activating factor (BAFF) – a new factor linking immunity to diet?
BIENERTOVÁ VAŠKŮ, Julie, Petr BIENERT, Filip ZLÁMAL, Josef TOMANDL, Martin FOREJT et. al.Basic information
Original name
B-cell activating factor (BAFF) – a new factor linking immunity to diet?
Authors
BIENERTOVÁ VAŠKŮ, Julie (203 Czech Republic, guarantor, belonging to the institution), Petr BIENERT (203 Czech Republic, belonging to the institution), Filip ZLÁMAL (203 Czech Republic, belonging to the institution), Josef TOMANDL (203 Czech Republic, belonging to the institution), Martin FOREJT (203 Czech Republic, belonging to the institution), Marie TOMANDLOVÁ (203 Czech Republic, belonging to the institution), Martin VAVŘINA (203 Czech Republic, belonging to the institution), Jana KUDĚLKOVÁ (203 Czech Republic, belonging to the institution), Zbyněk ŠPLÍCHAL (203 Czech Republic, belonging to the institution) and Anna VAŠKŮ (203 Czech Republic, belonging to the institution)
Edition
Central European Journal of Medicine, 2012, 1895-1058
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30000 3. Medical and Health Sciences
Country of publisher
Poland
Confidentiality degree
není předmětem státního či obchodního tajemství
Impact factor
Impact factor: 0.262
RIV identification code
RIV/00216224:14110/12:00060623
Organization unit
Faculty of Medicine
UT WoS
000304396200001
Keywords in English
BAFF; Obesity; Dietary composition; Diet; Anthropometry
Tags
International impact
Změněno: 20/8/2012 11:26, Mgr. Michal Petr
Abstract
V originále
B cell activation factor (BAFF) is a recently discovered member of the TNF ligand superfamily secreted by adipocytes, previously linked to autoimmune and lymphoproliferative disease. The aim of this study was to investigate the relationship between BAFF plasma levels and the non-modified, usual dietary composition as well as obesity-related anthropometric parameters in a cohort of 58 obese and non-obese Central-European Caucasian individuals. We found that BAFF had an independent predictive role for percentage of body fat; moreover, BAFF levels were correlated with waist and hip circumference. BAFF plasma levels were also significantly correlated with investigated dietary composition based on the 7-day food records, as the BAFF levels correlated with the percentage of energy derived from the carbohydrates and with energy derived from the dietary fat. Our results suggest that BAFF may play a role in linking the immune status and metabolic response to diet.