Publication Records

KEEGAN, Liam, Khadija HAJJI and Mary Anne O'CONNELL. Adenosine Deaminase Acting on RNA (ADAR) Enzymes: A Journey from Weird to Wondrous. Accounts of chemical research. WASHINGTON: American Chemical Society, 2023, vol. 56, No 22, p. 3165-3174. ISSN 0001-4842. Available from: https://dx.doi.org/10.1021/acs.accounts.3c00433.

O'CONNELL, Mary Anne, Michaela MUSILOVÁ and Barbora TRUKSOVÁ. RNA PhD Conference 2023. 2023.

HAJJI, Khadija, Jiří SEDMÍK, Anna CHERIAN, Damiano AMORUSO, Liam KEEGAN and Mary Anne O'CONNELL. ADAR2 enzymes: efficient site-specific RNA editors with gene therapy aspirations. RNA. Cold Spring Harbor: Cold Spring Harbor Laboratory Press, 2022, vol. 28, No 10, p. 1281-1297. ISSN 1355-8382. Available from: https://dx.doi.org/10.1261/rna.079266.122.

MARTINO, Fabiana, Nandan Mysore VARADARAJAN, Ana Rubina PERESTRELO, Václav HEJRET, Helena DURIKOVA, Dragana VUKIĆ, Vladimir HORVATH, Francesca CAVALIERI, Frank CARUSO, Waleed S ALBIHLAL, Andre P GERBER, Mary Anne O'CONNELL, Štěpánka VAŇÁČOVÁ, Stefania PAGLIARI and Giancarlo FORTE. The mechanical regulation of RNA binding protein hnRNPC in the failing heart. Science Translational Medicine. Washington: American Association for the Advancement of Science, 2022, vol. 14, No 672, p. 1-17. ISSN 1946-6234. Available from: https://dx.doi.org/10.1126/scitranslmed.abo5715.

QUIN, Jaclyn Elizabeth, Jiří SEDMÍK, Dragana VUKIĆ, Anzer KHAN, Liam KEEGAN and Mary Anne O'CONNELL. ADAR RNA Modifications, the Epitranscriptome and Innate Immunity. Trends in Biochemical Sciences. Cambridge (MA): Cell Press, 2021, vol. 46, No 9, p. 758-771. ISSN 0968-0004. Available from: https://dx.doi.org/10.1016/j.tibs.2021.02.002.

MAROOFIAN, Reza, Jiří SEDMÍK, Neda MAZAHERI, Marcello SCALA, Maha S. ZAKI, Liam KEEGAN, Reza AZIZIMALAMIRI, Mahmoud ISSA, Gholamreza SHARIATI, Alireza SEDAGHAT, Christian BEETZ, Peter BAUER, Hamid GALEHDARI, Mary Anne O'CONNELL and Henry HOULDEN. Biallelic variants in ADARB1, encoding a dsRNA-specific adenosine deaminase, cause a severe developmental and epileptic encephalopathy. Journal of Medical Genetics. London (UK): BMJ Publishing Group, 2021, vol. 58, No 7, p. 495-504. ISSN 0022-2593. Available from: https://dx.doi.org/10.1136/jmedgenet-2020-107048.

O'CONNELL, Mary. Generation of stable cell lines for the screening of inhibitors of the ADAR enzymes. Masarykova univerzita, 2021.

RENGARAJ, Praveenkumar, Aleš OBRDLÍK, Dragana VUKIĆ, Nandan Mysore VARADARAJAN, Liam KEEGAN, Štěpánka VAŇÁČOVÁ and Mary Anne O'CONNELL. Interplays of different types of epitranscriptomic mRNA modifications. RNA Biology. Philadelphia: Taylor & Francis Inc, 2021, vol. 18, S1, p. 19-30. ISSN 1547-6286. Available from: https://dx.doi.org/10.1080/15476286.2021.1969113.

KURKOWIAK, M., L. ARCIMOWICZ, E. CHRUSCIEL, Z. URBAN-WOJCIUK, I. PAPAK, Liam KEEGAN, Mary Anne O'CONNELL, J. KOWALSKI, T. HUPP and N. MAREK-TRZONKOWSKA. The effects of RNA editing in cancer tissue at different stages in carcinogenesis. RNA Biology. Philadelphia: Taylor & Francis Inc, 2021, vol. 18, No 11, p. 1524-1539. ISSN 1547-6286. Available from: https://dx.doi.org/10.1080/15476286.2021.1877024.

DENG, Patricia, Anzer KHAN, Dionna JACOBSON, Nagraj SAMBRANI, Leeanne MCGURK, Xianghua LI, Aswathy JAYASREE, Jan HEJÁTKO, Galit SHOHAT-OPHIR, Mary Anne O'CONNELL, Jin Billy LI and Liam KEEGAN. Adar RNA editing-dependent and -independent effects are required for brain and innate immune functions in Drosophila. Nature Communications. London: Nature Publishing Group, 2020, vol. 11, No 1, p. 1-13. ISSN 2041-1723. Available from: https://dx.doi.org/10.1038/s41467-020-15435-1.

TAN, Tiong Yang, Jiří SEDMÍK, Mark P. FITZGERALD, Rivka SUKENIK HALEVY, Liam KEEGAN, Ingo HELBIG, Lina BASEL-SALMON, Lior COHEN, Rachel STRAUSSBERG, Wendy K. CHUNG, Mayada HELAL, Reza MAROOFIAN, Henry HOULDEN, Jane JUUSOLA, Simon SADEDIN, Lynn PAIS, Katherine B. HOWELL, Susan M. WHITE, John CHRISTODOULOU and Mary Anne O'CONNELL. Bi-allelic ADARB1 Variants Associated with Microcephaly, Intellectual Disability, and Seizures. The American Journal of Human Genetics. University of Chicago Press for the American Society of Human Genetics, 2020, vol. 106, No 4, p. 467-483. ISSN 0002-9297. Available from: https://dx.doi.org/10.1016/j.ajhg.2020.02.015.

SINIGAGLIA, Ketty, Janka MELICHEROVÁ, Stanislav STEJSKAL, Liam KEEGAN and Mary Anne O'CONNELL. Elucidating the Biological Role of ADAR1 in the Innate immunity Response. In CEITEC PhD Conference. 2020.

KHAN, Anzer, Simona PARO, Leeanne MCGURK, Nagraj SAMBRANI, Marion C. HOGG, James Paul BRINDLE, Giuseppa PENNETTA, Liam KEEGAN and Mary Anne O'CONNELL. Membrane and synaptic defects leading to neurodegeneration in Adar mutant Drosophila are rescued by increased autophagy. BMC Biology. London: BMC, 2020, vol. 18, No 1, p. 1-16. ISSN 1741-7007. Available from: https://dx.doi.org/10.1186/s12915-020-0747-0.

WIATREK-MOUMOULIDIS, Dagmara Marta, Maria Elena CANDELA, Jiří SEDMÍK, Jan OPPELT, Liam KEEGAN and Mary Anne O'CONNELL. Activation of innate immunity by mitochondrial dsRNA in mouse cells lacking p53 protein. RNA. Cold Spring Harbor: Cold Spring Harbor Laboratory Press, 2019, vol. 25, No 6, p. 713-726. ISSN 1355-8382. Available from: https://dx.doi.org/10.1261/rna.069625.118.

SINIGAGLIA, Ketty, Dagmara WIATREK, Anzer KHAN, David MICHALÍK, Nagraj SAMBRANI, Jiří SEDMÍK, Dragana VUKIĆ, Mary Anne O'CONNELL and Liam KEEGAN. ADAR RNA editing in innate immune response phasing, in circadian clocks and in sleep. Biochimica et biophysica acta - Gene regulatory mechanisms. Amsterdam: Elsevier, 2019, vol. 1862, No 3, p. 356-369. ISSN 1874-9399. Available from: https://dx.doi.org/10.1016/j.bbagrm.2018.10.011.

O'CONNELL, Mary Anne. Nucleic Acids, Immunity and Genome Defence. 2018.

JANTSCH, M.F., A. QUATTRONE, Mary Anne O'CONNELL, M. HELM, M. FRYE, M. MACIAS-GONZALES, M. OHMAN, S. AMERES, L. WILLEMS, F. FUKS, A. OULAS, Štěpánka VAŇÁČOVÁ, H. NIELSEN, C. BOUSQUET-ANTONELLI, Y. MOTORIN, J.Y. ROIGNANT, N. BALATSOS, A. DINNYES, P. BARANOV, V. KELLY, A. LAMM, G. RECHAVI, M. PELIZZOLA, J. LIEPINS, I.H. KHOLODNYUK, V. ZAMMIT, D. AYERS, F. DRABLOS, J.A. DAHL, J. BUJNICKI, C. JERONIMO, R. ALMEIDA, M. NEAGU, M. COSTACHE, J. BANKOVIC, B. BANOVIC, J. KYSELOVIC, L.M. VALOR, S. SELBERT, P. PIR, T. DEMIRCAN, V. COWLING, M. SCHAFER, W. ROSSMANITH, D. LAFONTAINE, A. DAVID, C. CARRE, F. LYKO, R. SCHAFFRATH, S. SCHWARTZ, A. VERDEL, A. KLUNGLAND, E. PURTA, G. TIMOTIJEVIC, F. CARDONA, A. DAVALOS, E. BALLANA, D. O CARROLL, J. ULE and R. FRAY. Positioning Europe for the EPITRANSCRIPTOMICS challenge. RNA BIOLOGY. PHILADELPHIA: TAYLOR & FRANCIS INC, 2018, vol. 15, No 6, p. 829-831. ISSN 1547-6286. Available from: https://dx.doi.org/10.1080/15476286.2018.1460996.

BAJAD, P., MF JANTSCH, Liam KEEGAN and Mary Anne O'CONNELL. A to I editing in disease is not fake news. RNA BIOLOGY. PHILADELPHIA: TAYLOR & FRANCIS INC, 2017, vol. 14, No 9, p. 1223-1231. ISSN 1547-6286. Available from: https://dx.doi.org/10.1080/15476286.2017.1306173.

KEEGAN, Liam, Anzer KHAN, Dragana VUKIĆ and Mary O'CONNELL. ADAR RNA editing below the backbone. RNA. COLD SPRING HARBOR: COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT, 2017, vol. 23, No 9, p. 1317-1328. ISSN 1355-8382. Available from: https://dx.doi.org/10.1261/rna.060921.

GALLO, Angela, Dragana VUKIĆ, David MICHALÍK, Mary O'CONNELL and Liam KEEGAN. ADAR RNA editing in human disease; more to it than meets the I. Human Genetics. NEW YORK: SPRINGER, 2017, vol. 136, No 9, p. 1265-1278. ISSN 0340-6717. Available from: https://dx.doi.org/10.1007/s00439-017-1837-0.

TAN, M.H., Q. LI, R. SHANMUGAM, R. PISKOL, J. KOHLER, A.N. YOUNG, K.I. LIU, R. ZHANG, G.R. AMASWAMI, K. ARIYOSHI, A. GUPTE, Liam KEEGAN, C.X. GEORGE, A.R. AMU, N. HUANG, E.A. POLLINA, D.S. LEEMAN, A.R. USTIGHI, Y.P.S. GOH, A.C. HAWLA, Sal G. DEL, G. PELTZ, A.B. RUNET, D.F.C. ONRAD, C.E. SAMUEL, Mary Anne O'CONNELL, C.R. WALKLEY, K. NISHIKURA and J.B. LI. Dynamic landscape and regulation of RNA editing in mammals. Nature. LONDON: NATURE PUBLISHING GROUP, 2017, vol. 550, No 7675, p. 249-272. ISSN 0028-0836. Available from: https://dx.doi.org/10.1038/nature24041.

QUIN, J.E., I. BUJILA, M. CHERIF, G.S. SANOU, Y. QU, MV HOMANN, A. ROLICKA, S.B. SIRIMA, Mary Anne O'CONNELL, A. LENNARTSSON, M. TROYE-BLOMBERG, I. NEBIE and A.K.O. FARRANT. Major transcriptional changes observed in the Fulani, an ethnic group less susceptible to malaria. elife. CAMBRIDGE: ELIFE SCIENCES PUBLICATIONS LTD, 2017, vol. 6, SEP, p. nestránkováno, 19 pp. ISSN 2050-084X. Available from: https://dx.doi.org/10.7554/eLife.29156.

MANNION, Niamh, Fabiana ARIETI, Angela GALLO, Liam KEEGAN and Mary O´CONNELL. New Insights into the Biological Role of Mammalian ADARs; the RNA Editing Proteins. Biomolecules. Basel, Switzerland: MDPI AG, 2015, vol. 5, No 4, p. 2338-2362. ISSN 2218-273X. Available from: https://dx.doi.org/10.3390/biom5042338.

O´CONNELL, Mary. RNA modification and the epitranscriptome; the next frontier. RNA. New York: Cold Spring Harbor Laboratory Press, 2015, vol. 21, No 4, p. 703-704. ISSN 1355-8382. Available from: https://dx.doi.org/10.1261/rna.050260.115.

O´CONNELL, Mary, Niamh M. MANNION and Liam KEEGAN. The Epitranscriptome and Innate Immunity. PLOS GENETICS. SAN FRANCISCO: PUBLIC LIBRARY SCIENCE, 2015, vol. 11, No 12, p. 1-11. ISSN 1553-7404. Available from: https://dx.doi.org/10.1371/journal.pgen.1005687.