LF:ZLFA0521c Pharmacology I - p - Course Information

ZLFA0521c Pharmacology I - practice

Faculty of Medicine
Autumn 2008

Extent and Intensity

0/2/0. 2 credit(s). Type of Completion: z (credit).

Teacher(s)

Guaranteed by

prof. MUDr. Alexandra Šulcová, CSc.
Department of Pharmacology – Theoretical Departments – Faculty of Medicine
Contact Person: Renata Bláblová

Prerequisites (in Czech)

ZLPA0521c Pathology I - practice && ZLPF0521c Pathophysiol.I - practice

Course Enrolment Limitations

The course is offered to students of any study field.

Course objectives

From the course on pharmacology students are expected to obtain: a) from lectures and seminars: a clarification of integration in the field of biomedical subjects such as chemistry, physiology, molecular biology, pathology and pathological physiology enabling them to understand why, what mechanism by, and what conditions on, drugs and their combinations may elicit therapeutic, adverse, and toxic effects. They will acquire an orientation in drug classes according to their main therapeutic indications with an attention paid to common drug-drug interactions, too. Information on drug development process, rules of preclinical and clinical drug testing will also be given. b) from practicals: a training in practical skills in "pharmacological thinking" in cases of need to make a choice of drug, dosing regimen, rout and techniques of administration, and an elimination of adverse interactions with drugs simultaneously given.

Syllabus

Day 1: ANALGESICS. Opioid and nonopioid analgesics. Pharmacotherapy of pain. Prescription and practical use of analgesic preparations. NON-STEROIDAL ANTIINFLAMMATORY DRUGS, DRUGS USED IN GOUT. Classification and clinical use. GLUCOCORTICOIDS.
Day 2: PSYCHOTROPIC DRUGS Classification and terminology of psychotropics. Pharmacology of anxiolytics and hypnosedatives. Mechanism of action of benzodiazepines. Prescription of hypnosedatives and psychostimulants. H1-ANTIHISTAMINES. Histamine; pathophysiological role, H1- H2 - H3 receptors. Classification and clinical use of H1-antihistamines. Prescription of analgesics and hypnosedatives, respiratory tract.
Day 3: ANTIMICROBIAL AGENTS. Classification, mechanisms of action, combinations of antibiotics and chemotherapeutics. Co-talks. ANTIBACTERIAL CHEMOTHERAPEUTICS AND ANTIVIRAL AGENTS. Drugs acting in intestinal and urinary infections. Co-talks: Quinolones. Antiretroviral antivirotics. Antiherpetics. Antituberculous agents. SURFACE-ACTIVE DRUGS. Disinfectants, antiseptics, antifungal agents, other surface-active drugs. Prescription and use of selected surface-active preparations used in dermatology. Stomatological preparations. Getting ready for the final test: Revision: L 9 - 14 (local anesthetics, glucocorticoids, anticancer drugs, therapy of diabetes and ulcer disease.
Day 4: PHARMACOLOGY OF ANTICANCER DRUGS. IMMUNOLOGICALLY ACTIVE SUBSTANCES. Classification, mechanisms of action, clinical use of anticancer agents. Co-talks: Immunosuppression, immunomodulation. Getting ready for the next lesson: Revision: Prescriptions of local anesthetics, selected surface-active drugs, ready-made preparations. LOCAL ANAESTHETICS. Mechanism of action, classification, practical use and prescription.
Day 5: FINAL PRESCRIPTION TEST (classified). FINAL REVISING TEST (multiple-choice, classified). Co-talk: Therapy of anaphylactic shock. Work with PC - decision making in model therapeutical situations.

Literature

LINCOVÁ, Dagmar and Hassan FARGHALI. Základní a aplikovaná farmakologie. 2., dopl. a přeprac. vyd. Praha: Galén, 2007, xxiv, 672. ISBN 9788072623730. info
ZELENKOVÁ, Olga and Alexandra ŠULCOVÁ. Speciální stomatologická receptura pro praktická cvičení z farmakologie (Special stomatological prescriptions for practicals in pharmacology). 2. přepracované vydání. Brno: Masarykova univerzita v Brně, 2000, 30 pp. ISBN 80-210-2433-X. info
ŠULCOVÁ, Alexandra. Poznámky k přednáškám z farmakologie. 1. vyd. Brno: Masarykova univerzita, 1993, 97 s. ISBN 80-210-0640-4. info
DOSTÁLEK, Miroslav, Jan JUŘICA, Eva JANOŠTÍKOVÁ and Lucia ZAHRADNÍKOVÁ. Farmakokinetika (Pharmacokinetics). ČR: Grada, 2006, 220 pp. Farmacie a farmakologie. ISBN 80-247-1464-7. info
http://portal.med.muni.cz/modules.php?name=News&file=article&sid=367
RANG, H. P. Rang and Dale's pharmacology. 6th ed. [S.l.]: Churchill Livingstone, 2007, xiii, 829. ISBN 9780443069116. info
Lippincott's Illustrated Reviews : Pharmacology : Special Millennium Update Autor: Mary Julia Mycek M.J. Richard A. HarveyR.A., Champe P.C. 2000. ISBN: 0781724139
Pharmaceutical Practice. Winfield, A.J. & Richards, R.M.E., eds. Churchill Livingstone. , 3rd Ed. 2004. ISBN 0443 07206 X
Vybrané kapitoly z učebnice: http://books.google.cz/books?ct=result&q=farmakologie&lr=&as_brr=3&sa=N&start=0
Vybrané kapitoly z učebnice: http://books.google.cz/books?id=7lNQpLuETq4C&printsec=frontcover&dq=farmakologie&lr=&as_brr=3#PPA4,M1
Ritter, James M. - Lewis, Lionel D. - Mant, Timothy G.K. - Ferro, Albert. A Textbook of Clinical Pharmacology and Therapeutics, 5th Ed., Hodder Arnold, 2008. 465 s. ISBN 978-0-340-90046-8

Assessment methods

During the studying the student has to prove active knowledge of pharmacology acquired to get the credit. The student has to pass the prescription test and the final written exam - multiple-choice test.

Language of instruction

Czech

Further comments (probably available only in Czech)

The course is taught annually.
The course is taught: every week.

The course is also listed under the following terms Autumn 2006, Autumn 2007.

Enrolment Statistics (recent)
Permalink: https://is.muni.cz/course/med/autumn2008/ZLFA0521c

LF:ZLFA0521c Pharmacology I - p - Course Information

ZLFA0521c Pharmacology I - practice

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