BVGE061 Genetics

Faculty of Medicine
Spring 2011
Extent and Intensity
1/0. 2 credit(s). Type of Completion: zk (examination).
Teacher(s)
prof. MUDr. Julie Dobrovolná, Ph.D. (lecturer)
MVDr. Halina Matějová (assistant)
Guaranteed by
prof. MUDr. Julie Dobrovolná, Ph.D.
Department of Pathophysiology – Theoretical Departments – Faculty of Medicine
Contact Person: MVDr. Halina Matějová
Timetable
Mon 21. 2. to Sat 26. 3. Fri 8:00–10:30 B11/234
Prerequisites (in Czech)
BKBI011 Biology && BVPF0422p Pathophysiol II - lect && BVVP0533p Nutrition in health promotion and public health III - lecture
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The aim of this subject is to provide the students with the theoretical background they could benefit from in frame of forthcoming trend of construction of individual dietary programmes intended for different subsets of patients, on the grounds of determinantion of their genetic traits. The students will be introduced to the basic concepts of clinical genetics that relate to the nutritional determinants, as well as to the most frequent diseases, the therapy of which requires individualized nutritional practice.
Syllabus
  • Human genome and its structure, reaction to environmental factors. Mitochondrial and nuclear heredity. Gene and non-gene determination of biological characteristics from the nutritional perspective. Mutation types (exon, intron, promoter mutations, point mutations and their effects, insertion-deletion mutations, frameshift mutations). Monogenous and polygenous diseases. Relation of the multigene disease to the environment with respect to the qualitative and quantitative aspects of individual nutrition. Civilization diseases as a special sort of multigene disease. Genetics of obesity, stratification of patients based on conceivable genetic risk. Importance of DNA diagnostics in the practice of a dietitian. Nutritional counselling from the genetics perspective. Nutrigenomics.
Literature
  • Nutrition and genomics : issues of ethics, law, regulation, and communication. Edited by David Castle - Nola M. Ries. Boston: Elsevier/Academic Press, 2009, xvi, 293. ISBN 9780123741257. info
  • LUCOCK, Mark. Molecular nutrition and genomics : nutrition and the ascent of humankind. 1st ed. Hoboken: Wiley-Liss, 2007, xii, 140. ISBN 9780470081594. info
  • NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
  • HATINA, Jiří and Brian D. SYKES. Lékařská genetika : problémy a přístupy. Vyd. 1. Praha: Academia, 1999, 296 s. ISBN 8020007008. info
Teaching methods
lecture, semestral assay
Assessment methods
oral examination
Language of instruction
Czech
Further Comments
The course is taught annually.
The course is also listed under the following terms Autumn 2008, Spring 2009, Spring 2010, Spring 2012, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, Spring 2018, spring 2019, spring 2020, spring 2021, spring 2022, spring 2023, spring 2024, spring 2025.
  • Enrolment Statistics (Spring 2011, recent)
  • Permalink: https://is.muni.cz/course/med/spring2011/BVGE061