VSBC0221s Biochemistry I - seminar

Faculty of Medicine
Spring 2015
Extent and Intensity
0/2. 1 credit(s). Type of Completion: z (credit).
Teacher(s)
RNDr. Hana Bochořáková (seminar tutor)
Ing. Martina Čarnecká, Ph.D. (seminar tutor)
doc. RNDr. Jiří Dostál, CSc. (seminar tutor)
MUDr. Michaela Králíková, Ph.D. (seminar tutor)
Mgr. Milena Matejovičová, Ph.D. (seminar tutor)
Ing. Jitka Melounová, Ph.D. (seminar tutor)
RNDr. Hana Paulová, CSc. (seminar tutor)
Mgr. Jiří Slanina, Ph.D. (seminar tutor)
prof. RNDr. Eva Táborská, CSc. (seminar tutor)
doc. RNDr. Josef Tomandl, Ph.D. (seminar tutor)
Mgr. Marie Tomandlová, Ph.D. (seminar tutor)
PharmDr. Lenka Adámková, Ph.D. (assistant)
Mgr. Jana Gregorová, Ph.D. (assistant)
MUDr. Miroslava Hlaváčová, Ph.D. (assistant)
Lenka Nerudová (assistant)
doc. Mgr. Ondřej Peš, Ph.D. (assistant)
Ing. Jana Simonová, Ph.D. (assistant)
PharmDr. Kristýna Šebrlová, Ph.D. (assistant)
Guaranteed by
prof. RNDr. Eva Táborská, CSc.
Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Supplier department: Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Timetable of Seminar Groups
VSBC0221s/01: Thu 16:20–18:00 A16/213, J. Tomandl
VSBC0221s/02: Thu 16:20–18:00 A16/213, J. Tomandl
VSBC0221s/03: Thu 16:20–18:00 A16/213, J. Slanina
VSBC0221s/04: Thu 16:20–18:00 A16/213, J. Slanina
VSBC0221s/05: Thu 14:30–16:10 A16/213, J. Dostál
VSBC0221s/06: Thu 14:30–16:10 A16/213, J. Dostál
VSBC0221s/07: Thu 14:30–16:10 A16/213
VSBC0221s/08: Thu 14:30–16:10 A16/213
VSBC0221s/09: Mon 12:00–13:40 A16/213, H. Paulová
VSBC0221s/10: Mon 12:00–13:40 A16/213, H. Paulová
VSBC0221s/11: Tue 7:30–9:10 A16/213, J. Slanina
VSBC0221s/12: Tue 7:30–9:10 A16/213, J. Slanina
VSBC0221s/13: Tue 14:00–15:40 A16/213, H. Paulová
VSBC0221s/14: Tue 14:00–15:40 A16/213, H. Paulová
VSBC0221s/15: Mon 12:00–13:40 A16/213, M. Tomandlová
VSBC0221s/16: Mon 12:00–13:40 A16/213, M. Tomandlová
VSBC0221s/17: Tue 14:00–15:40 A16/213, M. Tomandlová
VSBC0221s/18: Tue 14:00–15:40 A16/213, M. Tomandlová
VSBC0221s/30: No timetable has been entered into IS.
VSBC0221s/31: No timetable has been entered into IS. J. Tomandl
VSBC0221s/32: No timetable has been entered into IS.
VSBC0221s/33: No timetable has been entered into IS.
VSBC0221s/34: No timetable has been entered into IS.
VSBC0221s/35: No timetable has been entered into IS.
VSBC0221s/36: No timetable has been entered into IS.
VSBC0221s/37: No timetable has been entered into IS. J. Tomandl
VSBC0221s/38: No timetable has been entered into IS.
VSBC0221s/39: No timetable has been entered into IS.
Prerequisites (in Czech)
VSLC011c Medical chemistry practice && VSLC011s Med. Chem. - seminar && ZC011 Handling chemical substances
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Seminars are complementary to Biochemistry lecture (VSBC021p). At the end of the course student understand and can describe the major metabolic pathways and their significance.
Syllabus
  • Water (properties, distribution), elektrolytes, nonelektrolytes, osmotic pressure, osmolality, osmolarity. Acid-base processes (pH, values of pH in organism). Buffers, Henderson-Hasselbalch eqution. Introduction to metabolism. Bases of bioenergetics (Gibbs energy, makroergnic compounds and their formation, chemical equilibrium and stady state). Redox equilibrium (elektrode potential, Nernst-Peters equation, biological redox systems). Introduction into the metabolism of cells (differences between prokatyotic and eukaryotic cell, compartmentation of metabolic processes, non-covalent interactions). Structure of haemoglobin and its relationship to the function. Hb types in the blood of healthy subjects, HbCO and MetHb, abnormal Hb types. Enzymes - reaction rate, progress curve, the Michaelis plot and Km, enzyme inhibition. Coenzymes, their relationship to vitamins. Written test I (Biochemical methods, haemoglobin, enzymology, coenzymes.) Membrane structure and assembly. Transport across membranes. Metabolism of glucose: Glycolysis under anaerobic and aerobic conditions and the oxidation of pyruvate. Gluconeogenesis. Glycogenesis and glycogenolysis. Metabolism of proteins. Common features of amino acid conversion. The synthesis of urea. Nitrogen balance. Important reactions in amino acid catabolism. Written test II (Membranes, transport across membranes, metabolism of saccharides and amino acids.) Biosynthesis and desaturation of fatty acids. The sources of essential fatty acids. Metabolism of triacylglycerols. Metabolism of phospholipids. Biosynthesis of eicosanoids. Peroxidation of lipids. Written test III (Metabolism of lipids.) The citric acid cycle. The respiratory chain and oxidative phosphorylation. Replication, transcription, proteosynthesis.
Teaching methods
Course is based on group discusion to the given topics. The outlines of discusion are in the recommended textbook. Complementary materials are available in section Study materials.
Assessment methods
Conditions for giving the course-unit credit Three short tests are written during the semester. Students that will obtain 52/75 points or more during the semester are not obliged to write the credit test. The other students will write the credit test with the 30 questions in the last week of the semester. The limit for passing the credit test is 14 points. All absences must be made up before writing the credit test. Students that will not fulfill this limit will be allowed to repeat the test once. Students that will not fulfill this requirement will not be given the course-unit credit. Obtaining of course-unit credits of practices and seminars is the pre-requisite for registration to the examination of Biochemistry I.
Language of instruction
Czech
Further Comments
Study Materials
The course is taught annually.
The course is also listed under the following terms Spring 2002, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Autumn 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, Spring 2013, Spring 2014, Spring 2016.
  • Enrolment Statistics (Spring 2015, recent)
  • Permalink: https://is.muni.cz/course/med/spring2015/VSBC0221s